Calcium release channels

Saito, A., et al., 1988. Ultrastrnctnre of die calcium release channel of sarcoplasmic redcnlnm. of Cell Biology 107 211-219. 

Fill M, Copello JA (2002) Ryanodine receptor calcium release channels. Physiol Rev 82 893-922... 

Reactive oxygen species modify the structure and function of the cardiac sarcoplasmic reticulum calcium release channel. Cardioscience 2, 19-25. 

In addition to the well-known iron effects on peroxidative processes, there are also other mechanisms of iron-initiated free radical damage, one of them, the effect of iron ions on calcium metabolism. It has been shown that an increase in free cytosolic calcium may affect cellular redox balance. Stoyanovsky and Cederbaum [174] showed that in the presence of NADPH or ascorbic acid iron ions induced calcium release from liver microsomes. Calcium release occurred only under aerobic conditions and was inhibited by antioxidants Trolox C, glutathione, and ascorbate. It was suggested that the activation of calcium releasing channels by the redox cycling of iron ions may be an important factor in the stimulation of various hepatic disorders in humans with iron overload. 

Malignant hyperthermia caused by mutant ryanodine receptor calcium release channels 723... 

Marx SO, Reiken S, Hisamatsu Y et al 2000 PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor) defective regulation in failing hearts. Cell 101 365-376... 

Skeletal muscle is activated by nerve impulses which induce Ca2+ release through the action of a voltage sensor, a protein also known as the dihydropyridine receptor,wx together with a calcium release channel known as the ryanodine... 

Tinker, A. and A. J. Williams, 1993, Probing the structure of the conduction pathway of the sheep cardiac sarcolpasmic reticulum calcium-release channel with permeant and impermeant organic cations,... 

Bidasee, K. R., Nallani, K., Yu, Y., Cocklin, R. R., Zhang, Y., Wang, M., Dincer, U. D., and Besch, H. R., Jr. (2003b). Chronic Diabetes Increases Advanced Glycation end Products on Cardiac Ryanodine Receptors/Calcium-Release Channels. Diabetes 52(7) 1825-36. 

Guner, S., Arioglu, E., Tay, A., Tasdelen, A., Aslamaci, S., Bidasee, K. R., and Dincer, U. D. (2004). Diabetes Decreases mRNA Levels of Calcium-Release Channels in Human Atrial Appendage. Mol... 

Lehnart, S. E., Wehrens, X. H., Laitinen, P. J., Reiken, S. R., Deng, S. X., Cheng, Z., Landry, D. W., Kontula, K., Swan, H., and Marks, A. R. (2004). Sudden Death in Familial Polymorphic Ventricular Tachycardia Associated with Calcium Release Channel (Ryanodine Receptor) Leak. Circulation 109(25) 3208-14. 

Ma, J., Hayek, S. M., and Bhat, M. B. (2004). Membrane Topology and Membrane Retention of the Ryanodine Receptor Calcium Release Channel. Cell Biochem Biophys 40(2) 207-24. 

Marks, A. R. (2001). Ryanodine Receptors/Calcium Release Channels in Heart Failure and Sudden Cardiac Death. . / Mol Cell Cardiol 33(4) 615-24. 

Scoote, M., and Williams, A. J. (2002). The Cardiac Ryanodine Receptor (Calcium Release Channel) Emerging Role in Heart Failure and Arrhythmia Pathogenesis. Cardiovasc Res 56(3) 359-72. 

Smith, J., Coronado, R., and Meissner, G. (1986). Single Channel Measurements of Calcium Release Channel from Skeletal Muscle Sarcoplasmic Reticulum. J. Gen. Physiol. 88 573-588. 

Smith, J. S., Imagawa, T., Ma, J., Fill, M., Campbell, K. P., and Coronado, R. (1988). Purified Ryanodine Receptor from Rabbit Skeletal Muscle is the Calcium-Release Channel of Sarcoplasmic Reticulum. J Gen Physiol 92(1) 1-26. 

Terentyev, D., Nori, A., Santoro, M., Viatchenko-Karpinski, S., Kubalova, Z., Gyorke, I., Terentyeva, R., Vedamoorthyrao, S., Blom, N. A., Valle, G., Napolitano, C., Williams, S. C., Volpe, P., Priori, S. G., and Gyorke, S. (2006). Abnormal Interactions of Calsequestrin with the Ryanodine Receptor Calcium Release Channel Complex Linked to Exercise-Induced Sudden Cardiac Death. Circ Res 98(9) 1151-8. 

Tester, D. J., Carturan, E., Dura, M., Reiken, S., Wronska, A., Marks, A. R., and Ackerman, M. J. (2006b). Molecular and Functional Characterization of Novel RyR2-Encoded Cardiac Ryanodine Receptor/Calcium Release Channel Mutations in Sudden Infant Death Syndrome. Heart Rhythm 3(5-Sl) S67. 

Tong, J., Oyamada, H., Demaurex, N., Grinstein, S., McCarthy, T. V., and MacLennan, D. H. (1997). Caffeine and Halothane Sensitivity of Intracellular Ca2+ Release Is Altered by 15 Calcium Release Channel (Ryanodine Receptor) Mutations Associated with Malignant Hyperthermia and/or Central Core Disease. J. Biol. Chem. 272(42) 26332-26339. 

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