Brenner, Sydney

I appreciate the helpful suggestions made by Dr. Alexander Rich, Prof. Christian Bauer, Dr. Walter Bodmer, Drs. Joseph and Celia Bonaventura, Dr. Sydney Brenner, Prof. Maur-izio Brunori, Dr. H. Frank Bunn, Prof. Patricia H. Clarke, Dr. Thomas E. Creighton, Dr. Richard E. Koehn, Dr. Arthur M. Lesk, Dr. Richard C. Lewontin, Dr. Robin N. Perutz, and Dr. Graham Shelton concerning this paper. To all these colleagues I wish to express my gratitude. 

The roundworms (Nematoda)127 129 have, in addition to the enteron (alimentary tract), a separate body cavity. Free-living nematodes abound in water and soil but many species are parasitic. They do enormous damage to plants and to some animal species. Trichina, hookworms1293, and filaria worms attack humans. However, in the laboratory the 1-mm-long, 810-cell nematode, Caenorhabditis elegans (Fig. 1-14) has become an important animal. In 1963 Sydney Brenner launched what has become a worldwide effort to make this tiny worm the equivalent in the animal kingdom of... 

The genetic code is the relation between the sequence of bases in DNA (or its RNA transcripts) and the sequence of amino acids in proteins. Experiments by Francis Crick, Sydney Brenner, and others established the following features of the genetic code by 1961 ... 

Bennett WM, Elzinga LW, Porter GA. Tubulointerstitial disease and toxic nephropathy. In The Kidney. Brenner BM, Rector EC, Jr, (editors). WB Saunders, Philadelphia. London. Toronto, Montreal, Sydney, Tokyo 1991 p. 1430-1496. 

Nobel Prize winner Sydney Brenner showed that a sequence of three nucleotide bases in a row encode each specific amino acid. RNA strands complementary to a DNA strand are responsible for the process called transcription, which is brought about by the action of the enzyme, RNA polymerase. 

The nervous system lies between genes and behavior. In his Nobel Prize lecture in 2002, geneticist Sydney Brenner said, Behavior is the result of a complex, ill-understood set of computations performed by nervous systems. It seems essential to decompose the question into two one concerned with the question of the genetic specification of (different) nervous systems and the other with the way nervous systems work to produce behavior. .. We are drowning in a sea of data and starving for knowledge. 

Nobel laureate Sydney Brenner, said, Modern biology has become so genocentric that we have forgotten that the real units of function and structure in an organism are cells and not genes. .. ... 

The genetics part the program was guided by Sydney Brenner, who subsequently won the 2002 Nobel Prize in physiology and medicine. Brenner showed that each three-nucleotide sequence of nucleotides in DNA encoded an amino acid. The nucleotide bases in DNA program the sequence of amino acids in peptides and proteins. 

South African-born British molecular biologist Sydney Brenner (1927- ) and French biochemist Frangois Jacob (1920- ) discover messenger... 

South African molecular biologist Sydney Brenner and... 

Sooner or later Ochoa had to tackle the problem of the genetic code. For several years he had in his hands the tool, that is, the polynucleotide phosphoryla, which made it possible to synthesize a variety of ribonucleic acids of Imown composition and, eventually, to decipher the code. Two more things were needed however the concept of messenger RNA, introduce by Francois Jacob and Jacques Monod in 1961. and Sydney Brenner s observation in the same year regarding the restricted spe( city of bacterial ribosomes in die translation of RNA messengers of different origin. 

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