Boronic acid hydrogels containing

Ehnas had detailed a temperature-sensitive copolymer, which contained boronic acid units its interaction with ARS and loss of flnorescence upon exposure to a series of analytes was discnssed. " However, boronic acid containing hydrogels that had been developed for electrophoresis applications (discnssed later) were reasoned to be snit-able in the stationary phase for a similar supported system. Thus, this platform allows a dye displacement assay to be performed. " ... 

Boronic Acid-Containing Hydrogels Synthesis and Their Applications... 

Synthesis and Properties of Boronic Acid-Containing Hydrogels... 

Scheme 10.1 Three routes to synthesize boronic acid-containing hydrogels (1) Polymerization of a boronic acid-containing monomer in the presence of a crosslinker (2) modification of a preformed network with boronic acid groups and (3) complexation between a boronic acid-bearing polymer and a diol-bearing polymer.

Another type of boronic acid-containing hydrogels is synthesized using Route 3 as shown in Scheme 10.1. In this route, crosslinking is achieved via the formation of boronate ester bonds between borax or a PBA-containing polymer and a polymer with diol groups. ... 

The glucose-sensitivity and other interesting properties of boronic acid-containing hydrogels lead to various applications, such as glucose sensing, self-regulated insulin release, and so on. 

Another important application of boronic acid-containing hydrogel is for drug release. The porous structure of hydrogels allows for loading of drugs into the gel matrix. In addition, their stimuli-responsivity allows for fine control over the drug release rate. 

Guan, Y., Zhang, Y.J., 2013. Boronic acid-containing hydrogels synthesis and their apphca-tions. Chem. Soc. Rev. 42 (20), 8106-8121. 

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