Biomimetic phosphate nanocomposites for bone-tissue regeneration

Worthwhile to stress is another inorganic component of bone water. With its 9 wt% of total bone mass, it is essential and crucial—and in bone-tissue engineering studies an often neglected component, because many studies include tests of 

Nanocomposites for Musculoskeletal Tissue Regeneration. http //dx.doi.or l0.1016/B978-l-78242 452 9.00013-3 Copyri t 2016 Elsevier Ltd. All rights reserved 

Besides these basic building blocks, bone cells populated on those structures are fundamental for keeping the bone material alive—osteoblasts and the mature osteo-cytes producing extracellular matrix (ECM) including the mineralized collagen fibrils and osteoclasts, the bone-resorbing cells [8]. Finally, bone-marrow stromal cells have the important role of differentiation into preosteoblasts—and in case of injury—play pivotal benefits in bone regeneration [9]. 

Murugan R, Ramakrishna S. Development of nanocomposites for bone grafting. Compos Sci Technol 2005 65(15-16) 2385-2406. 

Cell compatibility Human Human Human Human Human bone 

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Biomimetic phosphate nanocomposites for bone-tissue regeneration... 

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