Biology and biomedical research

During the past two decades, cell-biological and biomedical research has greatly benefited from innovations in fluorescence microscopy. Both the increase in the repertoire of fluorescence staining techniques at the (sub)cellular level and the development of a multitude of novel fluorescence microscopy techniques contributed significantly. 

Klostranec JM, Chan WCW. Quantum dots in biological and biomedical research recent progress and present challenges. Adv. Mat. 2006 18 1953-1964. 

Brace Lester, Ph. D., has more than 20 years of research experience in biological and biomedical research working in both industry and academic environments. In conjunction with several other faculty members at the University of Minnesota, he founded Knowledge Frontiers, which specializes in technology assessment and scientific due diligence. Over the years. Dr. Lester has been involved in studying the role of G-proteins in the adhesion, motility and invasion of metastatic cancer cells. 

Genome-wide gene expression analysis has become a tool that is widely used in biology and biomedical research. Technological improvements are likely to occur with respect to reduced sample input and/or more robust protocols for the preamplification of RNA, an increase of sensitivity, a better signal-to-noise ratio, the development of exon-specific probes to tackle the important issue of differentially spliced transcripts and of probes allowing the analysis of micro-RNAs. An equally important, although certainly more difficult, issue... 

The studies of interactions in the biological systems comprising genes, proteins, cellsa, tissues and respective networks leads to an integrative approach of biological and biomedical research. 

MOSSB AUER SPECTROSCOPY IN BIOLOGICAL AND BIOMEDICAL RESEARCH... 

Originally the tool of physicists and physical chemists, now with improved electronics the quadrupole mass spectrometer has become an essential instrument for biological and biomedical research. Originally described as a mass filter, it operates by using a combination of a quadrupole static electric field and a radiofrequency field which combine to focus an ion beam on a collector. 

GFP from the jellyfish Aequorea victoria and its artificial mutants are widely used in cell biology and biomedical research as genetically encoded fluorescent markers. In the past decade, a number of GFP-like proteins have been found in diverse marine creatures—corals, copepods and even lower chordates. Detailed biochemical and crystallographic studies have shown a great diversity of chromo-phore structures that ejqjlain the wide spectral variations in GFP-like proteins ". ... 

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