Biofunctionalization applications

FIGURE 8.6 Schematic representation of a new transducer for biosensor application based on a three-dimensional IDEA. Binding of molecules to the chemically modified and biofunctionalized transducer surface induces important conductivity changes between the electrodes, which can be monitored. (From Ram6n-Azcon, J. et al. 2008. Biosens. Bioelectron. 23 1367-1373. With permission.)... 

Although the fabrication and characteristics (material, size, biocompatibility, and others) of the desired SERS-encoded particles strongly depend on each specific application, all of them share some common requirements (a) the presence of an optical enhancer, (b) the addition of the SERS code, and (c) protection with a silica or polymer of the SERS code from leaching while providing a suitable surface for biofunctionalization [26, 27]. 

The prepared porous nanocrystalline Ti-6A1-4V, Ti-15Zr-4Nb and Ti-6Zr-4Nb alloys with electrochemically biofunctionalized surface could be a possible candidate for hard tissue implant applications. 

Those interested in the biomedical applications of ICPs can draw on the numerous advances in synthesis and processing to produce organic conductors with appropriate electronic and mechanical properties and yet have biofunctionality effectively integrated. 

Abstract The functionalization of synthetic polymers such as poly(ethylene terephthalate) to improve their hydrophilicity can be achieved biocatalytically using hydrolytic enzymes. A number of cutinases, lipases, and esterases active on polyethylene terephthalate have been identified and characterized. Enzymes from Fusarium solani, Thermomyces insolens, T. lanuginosus, Aspergillus oryzae, Pseudomonas mendocina, and Thermobifida fusca have been studied in detail. Thermostable biocatalysts hydrolyzing poly(ethylene terephthalate) are promising candidates for the further optimization of suitable biofunctionalization processes for textile finishing, technical, and biomedical applications. 

The biofunctionalization of PET with the aim to increase hydrophilicity of the hydrophobic polyester surfaee has wide-ranging applications from textile finishing to technical and medical fields. Among the biocatalysts with PET-hydrolyzing activity that have been reported so far, several have shown promising results for the biofunctionalization of PET as an alternative to presently used chemical or physical methods. However, an enzymatic treatment of PET materials requires highly active bioeatalysts and short treatment times to become industrially viable. Analysis of the effieieney of PET hydrolysis performed with biocatalysts at... 

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