Biochemistry stereochemistry

Parthasarathy, R., and Eisenberg, F., Jr., 1990, Biochemistry, stereochemistry, and nomenclature of the inositol phosphates, In Reitz, A.B. (ed.), Inositol Phosphates and Derivatives Synthesis, Biochemistry, and Therapeutic Potential. ACS Symposium Series 463. American Chemical Society, Washington, DC, pp. 1-19. 

A review on the preparation and separation of inositol tetrakisphosphates and the establishment of enantiomeric configuration by use of L-iditol dehydrogenase has appeared. The synthesis and biological evaluation of inositol derivatives as inhibitors of phospholipase C (PLC) has been reviewed. A review on the chemistry, preparation and enzymatic reactions of inositol phosphates and a review on the biochemistry, stereochemistry and nomenclature of inositol phosphates has also been reported. A part review on phosphonate analogues of myo-inositol triphosphate has appeared. ... 

Vanadate, dioxybis(oxamato)-bond-length ratios, 1,57 Vanadate, heptacyano-potassium salt structure, I, 72 Vanadate, hexafluoro-dipotassium salt history, I, 21 potassium salt history, 1,21 tripotassium salt history, 1,21 Vanadate, pentachloro-stereochemistry, 1,40 Vanadate, pentafluorooxy-stereochemistry, I, 50 Vanadates biochemistry, 3,456 calcium/magnesium ATPase inhibition, 6, 567 competition with phosphates physiology, 6,665 protonation, 3,1026 sodium pump, 6, 557 in uranium purification from ore, 6, 899 Vanadates, hexafluoro-, 3. 482,531 Vanadates, oxoperoxo-, 3,501 Vanadates, pentacarbonyl-, 3, 457 Vanadium biology, 6,665 determination, 1. 548 extraction... 

Bartnicki EW, CE Castro (1969) Biodehalogenation. The pathway for transhalogenation and the stereochemistry of epoxide formation from halohydrins. Biochemistry 8 4677-4680. 

The stereochemistry deals with the study of spatial structure of molecules and its effect on the physical and chemical properties of the compound. Until recently stereochemistry was thought to be purely a theoretical area of study but since it not only affects the properties but also controls the rate of reaction, it has assumed great practical importance. Now stereochemistry is applied to study physiological properties, biochemistry, molecular biology, pharmacy and even in medicine. So the scope of the subject has become enormous. Stereoisomerism is classified into two types. 

The series is intended for the advanced student, the teacher, and the active researcher. A background of the basic knowledge in the field of stereochemistry is assumed. Each chapter is written by an expert in the field and, hopefully, covers its subject in depth. We have tried to choose topics of fundamental importance aimed primarily at an audience of inorganic and organic chemists but involved frequently with basic principles of physical chemistry and molecular physics, and dealing also with certain stereochemical aspects of biochemistry. 

Alworth, W. L. Stereochemistry and Its Applications in Biochemistry Wiley-Interscience New York, 1972. 

This example is from biochemistry. It is a feature of biochemical reactions that enzymes almost always catalyse reactions in a completely stereospecific manner. They are able to distinguish between enantiotopic hydrogens because of the three-dimensional nature of the binding site (see Section 13.3.2). There are also occasions where chemical reactions are stereospecific refer to the stereochemistry of E2 eliminations for typical examples (see Section 6.4.1). 

Minor changes in the stereochemistry and substitution pattern of the steran skeleton result in vastly different yet specific physiological and pharmacological effects, which in turn influence developmental, metabolic, and behavioral phenomena. The organic chemistry and biochemistry of steroids is the subject of many excellent books and an enormous amount of research and patent literature. This chapter compares and contrasts the structure and mode of action of various steroids, their role in regulating hormonal secretion, and the timing of this regulatory action. 

Morrison and Boyd, 1983) is introduced in terms of the enzymic oxidation of ethanol. Here is an example where an important concept in stereochemistry arose from biochemistry and was subsequently incorporated into physical organic chemistry. 

Alworth, W. L. (1972) Stereochemistry and its Application in Biochemistry, Wiley-Interscience, New York... 

VIII. Insights into Stereochemistry and Its Relation to Biochemistry. 34... 

From H. Hirschmann, Newer Aqseeis of Enzymatic Stereochemistry in Comprehensive Biochemistry. Vol 12, M. Florkin and E. H. Stotz, sis. By permission of Elsevier Publishing Go.]... 

Hirschmann, H. Newer Aspects of Enzymatic Stereochemistry, in Comprehensive Biochemistry, Vol. 12, pp. 236ff. (Florkin, M., Stotz, G. H. eds). New York American Elsevier Publishing Co. 1964... 

KJ Weissman, M Timoney, M Bycroft, P Grice, U Hanefeld, J Staunton, PF Leadlay. The molecular basis of Celmer s rules the stereochemistry of the condensation step in chain extension on the erythromycin polyketide synthase. Biochemistry 36 13849-13855, 1997. 

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