322 / Biochemistry creatine

Rao, B. D. N. Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) smdies of nucleotide conformations in creatine kinase complexes effects due to weak nonspedftc binding. Biochemistry 1993,... 

Grossman, S.H., Pyle, J., and Steiner, R.J. (1981) Kinetic evidence for active monomers during the reassembly of denatured creatine kinase. Biochemistry 21, 6122. 

Hall, N. Addis, P. DeLuca, M. Mitochondrial creatine kinase. Physical and kinetic properties of the purified enzyme from beef heart. Biochemistry, 18, 1745-1751 (1979)... 

Lipskaya, T.Y. Mitochondrial creatine kinase properties and function. Biochemistry, 66, 1098-1111 (2001)... 

K.N. The 2.1 A structure of Torpedo californica creatine kinase complexed with the ADP-Mg -NOj-creatine transition-state analogue complex. Biochemistry, 41, 13861-13867 (2002)... 

Brindle, K., Braddock, P Fulton, S. (1990). 3IP NMR measurements of the ADP concentration in yeast cells genetically modified to express creatine kinase. Biochemistry 29,3295-3302. 

Hill, R.D. and Laing, R.R., Specific reaction of dansyl chloride with one lysine residue in rennin, Biochim. Biophys. Acta 132, 188-190, 1967 Chen, R.F., Huorescent protein-dye conjugates. I. Heterogeneity of sites on serum albumin labeled by dansyl chloride. Arch. Biochem. Biophys. 128, 163-175, 1968 Chen, R.F., Dansyl-labeled protein modified with dansyl chloride activity effects and fluorescence properties. Anal Biochem. 25, 412M16, 1968 Brown, C.S. and Cunningham, L.W., Reaction of reactive sulfydryl groups of creatine kinase with dansyl chloride. Biochemistry 9, 3878-3885, 1970 Hsieh, W.T. and Matthews, K.S., Lactose repressor protein modified with dansyl chloride activity effects and fluorescence properties. 

The association of muscle disease with a disturbance of creatine metabolism is a long-established contribution of biochemistry to this field, and the subject of much investigation in the past. It has been recognized for over half a century that, in contrast with normal adults, patients with nearly all types of muscle disease exhibit a creatinuria. Comprehensive... 

AcK acetate kinase AcP acetyl phosphate AdK adenylate kinase AP A p ,pn-di(adenosine 5 -) n-phosphate ARS aminoacyl tRNA synthetase ATP, ADP, AMP adenosine 5 -tri-, di-, monophosphate ATP-u-S (Sp)-adenosine 5 -0-(l-thiotriphos-phate), ATP-y-S adenosine 5 -0-(3-thiotriphosphate) CK carbamyl kinase CP carbamyl phosphate CrK creatine kinase CTP, CDP, CMP cytidine 5 -tri-, di-, monophosphate dATP, dAMP deoxyadenosine 5 -tri-, monophosphate DNA deoxyribonucleic acid AG change in free energy GK glycerol kinase GTP, GDP, GMP guanosine 5 -tri-, di-, monophosphate HK hexokinase IUB International Union of Biochemistry MCP methoxycarbonyl phosphate NTP, NDP, NMP nucleoside 5 -tri-, di-, monophosphate PC phosphocreatine PEP phosphoenol pyruvate P orthophosphate PK pyruvate kinase P polyphosphate PnK poly-... 

Plasma carnitine is monitored in LCFAOD, but whether or not it should be supplemented is an area of controversy [6], Some feel carnitine supplementation is indicated if plasma-free carnitine is low. Others feel that carnitine has not been shown to be beneficial and supplementation is not recommended [23], Other biochemistries are done to monitor the effect of the disease on the muscle (creatine kinase) and liver (glucose, liver function tests) (Box 24.5). 

Hagemann, H. Marcillat, O. Buchet, R. Vial, C., Magnesium-adenosine diphosphate binding sites in wild-type creatine kinase and in mutants Role of aromatic residues probed by Raman and infrared spectroscopies. Biochemistry 2000, 39(31), 9251-6. 

Perry SB, McAuliffe J, Balschi JA, Hickey PR, Ingwall JS (1988) Velocity of the creatine kinase reaction in the Neonatal rabbit heart role of mitochondrial creatine kinase. Biochemistry 27 2165-2172... 

Ng YQ, Ton SH, Khalid BAK (2009) Semm liver enzymes and creatine kinase levels in rats orally-administered with glycyrrhizic acid. Abstract Pg 91 35th annual conference Malaysian Society for Biochemistry and Molecular Biology... 

Ochoa s first publication in biochemistry (1929) was based on work in Juan Negrin s physiology laboratory. It was a method for the determination of total creatine in muscle. He had earlier completed a study on the effect of guanidine on the melanophores of the skin of the frog in the physiology laboratory of Noel Paton in Glasgow. 

Greenhaff, R, The nutritional biochemistry of creatine. JNutr Biochem, 11 610-618, 1997. 

Travers, F., Barman, T. E. Bertrand, R. (1979) Transient-phase studies on the creatine kinase reaction. European Journal of Biochemistry, 100, 149-55. 

Hunter, A. (1928), Creatine and Creatinine. Monographs on Biochemistry, London. 

Hooton, B. T., 1968, Creatine kinase isoenzymes and the role of thiol groups in the enzymic mechanism. Biochemistry 7 2063. 

---