DAMP 2 -deoxyadenosine

Adenine Deoxyadenosine Deoxyadenyiic acid Deoxyadenosine monophosphate (dAMP) Deoxyadenosine diphosphate (dADP) Deoxyadenosine triphosphate (dATP)... 

The adsorbability of these substances, measured by the differential capacity method [87,88] increases in the series adenine < dAMP < deoxyadenosine < ATP < AMP. 

ID, one-dimensional 2D, two-dimensional 3D, three-dimensional AMP, adenosine monophosphate CNDO, complete neglect of differential overlap COSY, correlation spectroscopy CPMG, Carr-Purcell-Meiboom-Gill NMR pulse sequence CT, constant time dAMP, deoxyadenosine monophosphate DFT, density functional... 

AcK acetate kinase AcP acetyl phosphate AdK adenylate kinase AP A p ,pn-di(adenosine 5 -) n-phosphate ARS aminoacyl tRNA synthetase ATP, ADP, AMP adenosine 5 -tri-, di-, monophosphate ATP-u-S (Sp)-adenosine 5 -0-(l-thiotriphos-phate), ATP-y-S adenosine 5 -0-(3-thiotriphosphate) CK carbamyl kinase CP carbamyl phosphate CrK creatine kinase CTP, CDP, CMP cytidine 5 -tri-, di-, monophosphate dATP, dAMP deoxyadenosine 5 -tri-, monophosphate DNA deoxyribonucleic acid AG change in free energy GK glycerol kinase GTP, GDP, GMP guanosine 5 -tri-, di-, monophosphate HK hexokinase IUB International Union of Biochemistry MCP methoxycarbonyl phosphate NTP, NDP, NMP nucleoside 5 -tri-, di-, monophosphate PC phosphocreatine PEP phosphoenol pyruvate P orthophosphate PK pyruvate kinase P polyphosphate PnK poly-... 

Adenosine kinase catalyzes phosphorylation of adenosine and deoxyadenosine to AMP and dAMP, and de-oxycytidine kinase phosphorylates deoxycytidine and 2 -deoxyguanosine to dCMP and dGMP. 

Adenine Adenosine-5 -phosphate (AMP) Deoxyadenosine-5 -phosphate (dAMP)... 

This enzyme [EC 2.7.1.76] catalyzes the reaction of ATP with deoxyadenosine to produce ADP and dAMP. The enzyme will also utilize deoxyguanosine as a substrate. In some systems, this enzyme may be identical with de-oxycytidine kinase. 

DNA, the genetic material, is a long, unbranched polymer containing the four de-oxynucleoside monophosphates deoxyadenosine monophosphate (dAMP), de-oxythymidine monophosphate (dTMP), deoxyguanosine monophosphate (dGMP),... 

The amount of zinc(II) ions bound to the polymer was quite elegantly determined by the use of a zinc(II) selective fluorophore developed by the same group. [3] Adsorption of phosphates such as 5 -dAMP and 4-NPP, adenosine 3, 5 -cyclic-monophosphate (3, 5 -cAMP) and the corresponding dephosphorylated compounds, deoxyadenosine (dA) and 4-nitrophenol (4-NP) was studied. The polymer was stirred in a solution containing the studied guest in a buffered aqueous solution. The adsorption efficiency was determined by the decrease of the guest molecule concentrations by UV measurement. 

CMRL CMS CPE dAMP, dTMP Connaught Medical Research Laboratories Calgon metasilicate cytopathic effect deoxyadenosine monophosphate, deoxythymidine monophosphate, etc. 

A-residue, G-residue etc. or more simply dA, dG (or A, G etc. where there is no possibility of confusion with the ribonucleotides, for example as in a DNA sequence) pdT etc. dTMP, dAMP etc. rATP, rCTP etc. A deoxyadenosine (deoxyguanosine) monophosphate either at one end, or within, a polynucleotide chain and linked to the adjacent nucleotide(s) by phosphodiester bond(s) deoxythymidine 5 -monophosphate the deoxynucleoside 3 -monophosphate the ribonudeoside triphosphates, adenosine triphosphate, cytidine triphosphate etc. 

D 3- D da Da daf dAMP symmetry group [e.g., D3 also used in names, such as (+)-D3-tris-homocubane] two-dimensional (also 2D) three-dimensional (also 3D) deca or deka (10) dalton dry ash free 2 -deoxyadenosine 5 -monophosphate or phosphate (the A can be replaced with C, G, U, etc.)... 

Deoxyadenosine-5-monophosphate (3 -dAMP) incorporation into RNA by RNAP causes chain termination (no free 3 -hydroxyl therefore no further elongation possible)... 

Adenine (A) Deoxyadenosine Guanine (G) Deoxyguanosine Thymine (T) Thymidine Cytosine (C) Deoxycytidine Deoxyadenylate (dAMP) Deoxyguanylate (dGMP) Thymidylate (TMP) Deoxycytidylate (dCMP)... 

The reducibility of adenine is not substantially influenced when it is bound in dinucleotides [80]. The half-wave potential becomes more negative in the series deoxyadenosine monophosphate (dAMP) adenine < adenosine < deoxyadenosine < adenosine monophosphate < adenosine triphosphate (ATP). The difference in E n between AMP and adenine is only 25 mV. 

In general, adsorption of neutral molecules at the electrode surface depends on the electrode potential, and the amount adsorbed shows a so-called bell-type dependence on the potential having a maximum at pzc. The adsorption of adenine is regarded as an example of such a case. Contrary to this, deoxyadenosine and dAMP give no simple bell-type A/ /i o — relations (see Fig. 18B and C) that is, the decrease in A7 /Iio is not as significant as for adenine at potentials more positive than —0.1 V. 

In the absence of ADA activity, both adenosine and deoxyadenosine will accumulate. When deoxyadenosine accumulates, adenosine kinase can convert it to dAMP. Other kinases will allow dATP to then accumulate within the lymphocyte. Why specifically the lymphocyte The other cells of the body are secreting the deoxyadenosine they cannot use, and it is accumulating in the circulation. As the lymphocytes are present in the circulation, they tend to accumulate this compound more so than cells not constantly present within the blood. As dATP accumulates, ribonucleotide reductase becomes inhibited, and the cells can no longer produce deoxyribonucleotides for DNA synthesis. Thus, when cells are supposed to grow and differentiate in response to cytokines, they cannot, and they die. 

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