Bioassay, brine shrimp

The brine shrimp (Anemia salina) has been evaluated as an alternative to the mouse bioassay for use in cyanobacterial toxicity screening assays." " " As in the... 

Price KS, Waggy GT, Conway RA. 1974. Brine shrimp bioassay and seawater BOD of petrochemicals. J Water Pollut Contr Fed 46 63-77. 

McLaughlin, J.L. Crown gall tumours on potato discs and brine shrimp lethality two simple bioassays for higher plant screening and fractionation, in Methods in Plant Biochemistry, Hostettmann, K., Ed., Vol. 6, Academic Press, London, 1-32, 1991. 

Lieberman, M. A Brine Shrimp Bioassay for Measuring Toxicity and Remediation of Chemicals, Chem. Educ. 1999, 76, 1689-1691. Persinger, H. Expanded Emphasis on Toxicology in an Environmental Chemistry and Engineering Course, 214th Am. Chem. Soc. Nat. Meet.,... 

Zootoxicity of hemoiedemosides A (72) and B (73) from Hemoiedema spectabilis and their desulfated derivative 74 were evaluated using the brine shrimp Artemia salina larvae mortality bioassay [51]. Hemoiedemoside A (72) showed a noteworthy toxicity in this assay (LC50 47.5 ppm). Hemoiedemoside B (73) was 2 times less active (LC50 47.5 ppm) than glycoside 72 and nearly 10 times more active than the desulfated derivative 74 (LC50... 

Meyer, B.N., Ferrigni, N.R., Jacobsen, L.B., Nichols, D.E. and McLaughlin, J.L. (1982). Brine Shrimp. A convenient general bioassay for active plant constituent. Planta Medica, 45 35-38. 

NR Ferringi, JL McLaughlin, RG Powel, CR Smith. Use of potato disk and brine shrimp bioassay to detect activity and isolate piceatanol as the anti-leukemic principle from the seeds of Euphobia lagascae. J Nat Prod Al 347-352, 1984. 

The air-dried ground roots of Karwinskia parvifolia were successively extracted with petroleum (bp 60-80), EtOAc and MeOH at room temperature through bioassay guide fractionation (34). Only the two first extracts showed biological activity (brine shrimp test) and were further... 

Two common in-house bioassays to screen for metabolites exhibiting general cytotoxicity, the fertilized sea urchin egg cytotoxicity assay and the brine shrimp lethality assay, were used to identify bioactive diterpene metabolites in two soft coral species collected from Sodwana Bay and Ponto do Ouro respectively. Sodwana Bay specimens of Sarcophyton... 

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