Binding classification

Idarubicin, an antibiotic with antineoplastic activity (12 mg/m2 daily by slow IV injection), is indicated in the treatment of acute myelocytic leukemia in adults, including fragment, antigen-binding, classification M through M , in combination with other approved antileukemic agents. 

This structure encoding method has been applied both for the classification of a data set comprising 31 corticosteroids, for which affinity data were available in the literature, binding to the corticosteroid-binding globulin (CBG) receptor, and for the simulation of infrared spectra [28, 29). 

The U.S. Eood and Dmg Administration (EDA) adopted a legally binding standard, which took the form of a performance standard for laser products (56,57). The standard provides a classification scheme for lasers similar to the ANSI classification. AH lasers sold after August 2, 1976 must comply with its provisions. The standard requires incorporation of safety-related labeling and protective equipment according to the class of the laser. The primary impact of the EDA standard is on laser manufacturers and scientific supply firms. 

Table 1. Classification of Binding Mechanisms According to Rumpf ...

In this work the state-of-the-art and perspectives of column characterization and compai ison have been presented and discussed. All information about physico-chemical properties of RP HPLC Cl8 and C8 columns as porosity, average surface area, free silanol concentration, binding ligand density and others, were summarized. The points of views about column classifications, its advantages and disadvantages were discussed. It was shown that Cl8 and C8 HPLC column classification processes do not allow selecting the column with the same or preai range selectivity. 

Macropolycyclic ligands, 2,942 classification, 2,917 metal complexes binding sites, 2, 922 cavity size, 2,924 chirality, 2, 924 conformation, 2,923 dimensionality, 2, 924 electronic effects, 2, 922 shaping groups, 2,923 structural effects, 2,922 molecular cation complexes, 2,947 molecular neutral complexes, 2,952 multidentate, 2,915-953 nomenclature, 2,920 Macro tetrolide actins metal complexes, 2,973 Macrotricycles anionic complexes, 2,951 cylindrical... 

More than 50 proteins have been discovered in the cytosol of nonmuscle cells that bind to actin and affect the assembly and disassembly of actin filaments or the cross-linking of actin filaments with each other, with other filamentous components of the cytoskeleton, or with the plasma membrane. Collectively, these are known as actin-binding proteins (ABPs). Their mechanisms of actions are complex and are subject to regulation by specific binding affinities to actin and other molecules, cooperation or competition with other ABPs, local changes in the concentrations of ions in the cytosol, and physical forces (Way and Weeds, 1990). Classifications of ABPs have been proposed that are based on their site of binding to actin and on their molecular structure and function (Pollard and Cooper, 1986 Herrmann, 1989 Pollard et al., 1994). These include the following ... 

A machine-learning method was proposed by Klon et al. [104] as an alternative form of consensus scoring. The method proved unsuccessful for PKB, but showed promise for the phosphatase PTPIB (protein tyrosine phosphatase IB). In this approach, compounds were first docked into the receptor and scored using conventional means. The top scoring compounds were then assumed to be active and used to build a naive Bayes classification model, all compounds were subsequently re-scored and ranked using the model. The method is heavily dependent upon predicting accurate binding... 

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