Basic Thesis

In contrast to the classical view of medicine, we propose the following approach to understanding disease. 

The normal biochemical systems permit the individual to adapt 

The failure to adapt to environmental factors results in disease. A disease-producing environmental factor is termed a stress factor or a stress.  

The failure to adapt to an environmental factor implies failure of metabolic control, i.e., the presence of a metabolic defect. As has already been developed in the previous section, the metabolic defect should be traceable to some abnormality in a specific enzyme or protein. 

A metabolic defect may be so profound that it is lethal regardless of environmental conditions. A metabolic defect may be latent so that it does not become manifest until there is exposure to an unusual or novel stress. A metabolic defect may be trivial so that it never causes clinical disease in any environment. 

---

In summary, these descriptive results support our basic thesis that the impact of satisfaction and customer loyalty on customer profitability is moderated by situation-specific factors encountered by the vendor. 

We now describe an experiment that tested our basic thesis that people select actions diagnostic of favourable outcomes, even if it is clear that the action does not facilitate the outcome. Self-report measures were also included to test the notion that, even if people do engage in the diagnostic behaviour, the favourable diagnosis would be made primarily by subjects who deny that the action was purposefully... 

The basic thesis of this paper, the displacement of interface states by strongly chemisorbed species, is also applicable to grain boundaries. 

A. THE BASIC THESIS PARAGRAPH INCLUDES AN INTRODUCTION, A THESIS STATEMENT, AND A BRIEF DESCRIPTION OF THE POINTS THAT WILL BE DISCUSSED. 

The basic thesis of Zisman s work was that the contact angle of a liquid on a solid reflects in some way the chemical constitution of the solid surface. He took the point of view Langomuir that the range of forces acting at the surface of a non-polar solid are short of the order of a few nanometers. Therefore, the contact angle must reflect the properties and in some fashion the actual composition of the surface of the solid. In this context, contact angle measurements are highly sensitive to the outer most chemical characteristics of solid surfaces. 

The basic thesis of this review is that the disordered materials show certain universal features in their electronic structure. They are best summarized in the Mott-CFO model there are bands of allowed states within the bands critical energies — mobility edges — occur at which the nature of the states changes abruptly from localized in the tails of the band to extended in the interior of the band bands may overlap although all the extended states... 

The basic thesis has served as the stimulus for a large number of studies directed towards the prediction of protein three-dimensional structures from their amino-acid sequences alone. Implicit in most of the predictive methods investigated are two concepts (i) that there is in the protein the clearly-observed hierarchical structural arrangement (primary structure - secondary structure - secondary aggregates or super-secondary structure - domains - total structure) which has already been discussed in the previous section and (ii) that the folding process of a random chain to give the stable native structure is kinetically-controlled and that it proceeds via a characteristic and predictable pathway. This pathway is visualized as requiring nucleation at various sites around which the subsequent... 

Our basic thesis is that compliance with environmental regulations can be achieved through use of a model for the detection, correction, mitigation, and prevention of environmental compliance and management... 

A combination of the promoting effects of Lewis acids and water is a logical next step. However, to say the least, water has not been a very popular medium for Lewis-acid catalysed Diels-Alder reactions, which is not surprising since water molecules interact strongly with Lewis-acidic and the Lewis-basic atoms of the reacting system. In 1994, when the research described in this thesis was initiated, only one example of Lewis-acid catalysis of a Diels-Alder reaction in water was published Lubineau and co-workers employed lanthanide triflates as a catalyst for the Diels-Alder reaction of glyoxylate to a relatively unreactive diene . No comparison was made between the process in water and in organic solvents. 

At the Installation, Sakharov worked with many colleagues, in particular Yakov Zcldnvich and David Frank-Kamenetskii. Sakharov made key contributions to the Soviets first full-fledged H-bomb, tested in 1955. He also made many contributions to basic physics, perhaps the most important being his thesis that the universe is composed of matter (rather than all matter having been annihilated against antimatter) is likely to be related to charge-parity (CP) noninvariance. 

Muller must have been disappointed to learn that he was not the discoverer of DDT. Sixty-five years earlier and seventy miles down the Rhine River, an Austrian graduate student at the University of Strasbourg had synthesized the compound as part of his chemistry doctoral thesis. Although Othmar Zeidler described many of DDT s properties and developed the method used to make it commercially, he overlooked the compound s insecticidal powers. And because DDT was not used to make dyestuffs, it was soon forgotten. Thus, when Geigy took out the basic Swiss patent in March 1940, it was for DDT s use as an insecticide. 

In this chapter we discuss techniques for program verification and their mathematical justification. The basic idea behind these methods was originally presented by Floyd mathematical formulations and logical justifications were developed by Cooper and Manna, and others, and continued in King s Ph.D. thesis in which he presented the development of a partial implementation for these techniques. A sanewhat different axiomatic approach has been pursued by Hoare et al. The reader who has never made acquaintance with the formalism of the first order predicate calculus should at this point turn to Appendix A for a brief and unrigorous exposition of the material relevant to this chapter. 

The thesis that all lipid-soluble compounds basically penetrate faster than water-soluble ones cannot be supported in this absolute form. A lipophilic agent can penetrate faster or slower or at the same rate as a hydrophilic agent, depending on the vehicle used. 

These studies were supported by the Basic Research Fund, American Institute of Baking and constitute the Ph.D. thesis, Kansas State University (1984), of Bohannon. 

There is one method that is based on a time-domain model. It was developed at Shell Oil Company (C, R. Cutler and B. L. Kamaker, Dynamic Matrix Control A Computer Control Algorithm, paper presented at the 86th National AlChE Meeting, 1979) and is called dynamic matrix control (DMC). Several other methods have also been proposed ihat are quite similar. The basic idea is to use a time-domain step-response model of the process to calculate the future changes in the manipulated variable that will minimize some performance index. Much of the explanation of DMC given in this section follows the development presented by C. C. Yu in his Ph.D. thesis (Lehigh University, 1987). 

Treshow has developed the thesis that foliar injury is a useful criterion in the identification and analysis of air pollution effects on vegetation and presented some basic concepts for use in field evaluation. 

Some economists, such as 1993 Nobel laureate Douglass North, argue that the invention of intellectual property and its protection caused an explosion in creativity that was the basic force behind the Industrial Revolution (Hall and Jones 1999). As Charles Jones observed, sustained economic growth is a very recent phenomenon - it began with the Industrial Revolution in Britain in the 1760s - and the thesis of Douglass North and a number of other economic historians is that the development of intellectual property rights, a cumulative process that occurred over centuries, is responsible... 

---