Bacteria ascorbic synthesis

Nearly all vitamins are associated in some way with the normal growth function as well as with the maintenance and efficiency of living things. Various species are capable of synthesizing some of the vitamins from precursors llial are present in tlie body. Synthesis is frequently by way of intestinal bacteria. In the case of vitamin D, substances in the skin combine with ultraviolet radiation from sunlight to yield the essential substance. Some vitamins, such as vitamin C. are specific, singular substances—in this case ascorbic acid. With other vitamins, there is a range of related compounds, as exemplified by the D, F., and K vitamins. 

Biotin -member of the B-complex family Water soluble Metabolism of fats synthesis of ascorbic acid healthy skin hair balding and greying. Soya beans, brown rice, nuts, fruit, brewer s yeast and milk. It can be synthesised by intestinal bacteria. 100 pg No... 

The starting point for synthesis of vitamin C is the selective of oxidation of the sugar compound D-sorbit to L-sorbose MsingAcetobacter sub-oxidans bacteria. L-sorbose is then converted to L-ascorbic acid, better known as vitamin C. 

These generalizations are illustrated by the recent synthesis of L-ascorbic acid glucosides 11 and 12 (16), The monosodium salt of ascorbic acid in N,N-dimethylformamide (DMF) affords exclusively the 03 monoalkylated derivative 9 on alkylation with 2,3,4,6-tetra-O-a-n-glucopyranosyl bromide. To obtain the 02 glucosylated derivative 10, under the same conditions, required the protection of the C3 hydroxyl as a methyl ether. Several workers have reported the biosynthesis of ascorbic acid glucosides in bacteria (17) however, the structure and position of glucosylation in these compounds has not been unambiguously determined. 

Poultry. More than 100 papers have been published on the value of supplementing diets of farm animals with L-ascorbic acid. The overall results are at times controversial. Enhancement of poultry growth has been reported by several workers using purified (144,145) and practical (146,147,148) rations and not by others (149), the general interpretation being that the ascorbic acid does not function directly but indirectly, involving a protective action or improved utilization of other nutrients. Added dietary ascorbic acid has been reported to stimulate synthesis or liberation of folic acid by intestinal bacteria, to aid in its conversion to folacin (146,150,151,152), to reinforce antibiotics in high... 

Both starting materials were prepared enzymatically. Genetically engineered bacteria have been used to convert glucose to 2-keto-L-gulonic acid, eliminating four steps in the synthesis of ascorbic acid (vitamin C).253... 

Vitamin C Vitamin G, ascorbic add, helps destroy invading bacteria aids the synthesis and activity of interferon, which prevents the entry of viruses into cells and combats the ill effects of toxic substances, including drugs and pollutants. It also aids in the synthesis of collagen, which is present in cartilage, bone, tendons, and connective tissue, and is therefore important in the healing of wounds and for infants and pregnant women. In addition, vitamin G is an antioxidant. 

Preparation, The biochemical oxidation of sorbitol is the most convenient source of this sugar, which, as an intermediate in the commercial synthesis of ascorbic acid, is prepared in large quantities by this method. The early researches by Bertrand 100) showed that sorbitol may be oxidized by sorbose bacteria Acetobacter xylinum Adrian Brown) to L-sorbose. Yields of 50 to 75 % are reported. By carrying out the fermentation with Acetobacter suboxydans in rotating drums instead of utilizing surface cultures of Bertrand s organism, yields of over 90% are obtained 101),... 

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