Bacillus megaterium

Bacillus fragilis Bacillus lichemformis Bacillus megaterium Bacillus polymyxa Bacillus sphaericus... 

Oxeta.nocins, Oxetanocia A (49), formerly oxetanocia, is the first naturally occurring oxetanose derivative and is isolated from Bacillus megaterium (1,145). It inhibits gram-positive bacteria, herpes vimses, and human immunodeficiency vims (HIV) (146). The chemical synthesis of (49) and several derivatives has been reported (147). 

Polyether Staph, aureus KXQXh Sarcina antibiotic No. 6538P lutea 9341 Bacillus sp. E 27859 Bacillus suhtilis 558 Bacillus megaterium 8011 Bacillus sp. EA 27860 Mycobacterium phlei 355 Streptomyces cellulosae 3313 Eaecilomyces varioti 26820... 

Bacillus megaterium Bovista plumbia Escherichia coii Kiuyvera citrophila Pseudomonas melanogenum... 

The latter two points usually tip the balance in favour of using purified enzymes. Ideally the enzyme should be easy to isolate. The penicillin acylase from Bacillus megaterium is, for example, an extracelluar enzyme and can be readily absorbed into bentonite. 

Maridomycin III 4"-0-Depropionyl-maridomycin II 18-Dihydromarido-mycin III, 4"-Depropionyl-maridomycin III and 18-Dihydro-4"-depropio nylmaridomycin III Bacillus megaterium Streptomyces pristinaespiralls Streptomyces sp i... 

BAL—see Propan-l-ol, 2,3-dimercapto-Bacillus cereus calcium transport, 6,572 Bacillus megaterium calcium efflux, 6, 570 calcium transport, 6,572 sporulation zinc transport, 6, 572 Bacillus spp. sodium ions, 6, 559 sporulation... 

Among other polysaccharides studied were those elaborated by Neisseria per-flava (starch-type polysaccharide), Polytomella coeca (a starch richer in amy-lopectin than most natural starches), Pseudomonas morsprunorum (Wormald) (levan), Acetobacter acetigenum (cellulose), Aerobacter aerogenes (NCTC 8172) (Klebsiella Type 164), Bacillus megaterium. Bacterium pruni, and Bacterium prunicola (polyfructoses of the levan type). 

Hydroxylation of long-chain carboxylic acids, amides, and alcohols—but not the esters or the corresponding alkanes—at the w-l, (0-2, and (o-3 positions by a soluble enzyme system from Bacillus megaterium (Miura and Fulco 1975 Narhi and Fulco 1986,1987). 

Hydroxylation of progesterone and closely related compounds at the 15-(3 position by cell extracts of Bacillus megaterium (Berg et al. 1976). 

Berg A, JA Gustafsson, M Ingelman-Sundberg, K Carlstrdm (1976) Characterization of a cytochrome P-450-dependent steroid hydroxylase present in Bacillus megaterium. J Biol Chem 251 2831-2838. 

Miura Y, AJ Fulco (1975) u-l, co-2, and co-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium. Biochim Biophys Acta 388 305-317. 

Narhi LO, AJ Fulco (1986) Characterization of a catalytically self-sufficient 119,000-Dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium. J Biol Chem 261 7160-7169. 

Strains of Bacillus megaterium and Streptomyces sp. strain 179 transformed vanillate to guaiacol by decarboxylation (Crawford and Olson 1978), and the gene cluster encoding decarboxylation in Streptomyces sp. strain m D7 has been characterized (Chow et al. 1999). 

Spiegelman, Aronson, and Fitz-James found that digestion of protoplasts of Bacillus megaterium led to the liberation of nuclear bodies of the protoplasts. Such bodies were collected by centrifugation for 5 min. at 10,000 x g. 

Gong, P.-F., Xu, J.-H, Tang, Y.-F. and Wu, H.-Y. (2003) Improved catalytic performance of Bacillus megaterium epoxide hydrolase in a medium containing Tween-80. Biotechnology Progress, 19, 652-654. 

Gong, P.-F. and Xu, J.-H. (2005) Bio-resolution of a chiral epoxide using whole cells of Bacillus megaterium ECU1001 in a biphasic system. Enzyme and Microbial Technology, 36, 252-257. 

The Gram-positive bacteria Bacillus subtilis, Bacillus megaterium and Bacillus brevis are also used for heterologous expression. Terpe [13] presented a table with some pharmaceutically and industrially relevant proteins expressed with this host. It is the most used prokaryotic host after... 

The polyesters synthesized by microorganisms were first investigated by Lemoigne, who isolated the reserve polymers in Bacillus megaterium in 1925 and identified the polymer to be poly(3-hydroxybutyrate), poly(3HB) [1]. The chemical structure of poly(3HB) is shown in Fig. 1. 

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