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Oxetanocin from Bacillus megaterium

Oxetanocins. Oxetanocin A (49), formerly oxetanocin, is the first naturally occurring oxetanose derivative and is isolated from bacillus megaterium (1,145). It inhibits gram-positive bacteria, herpes viruses, and human immunodeficiency virus (HIV) (146). The chemical synthesis of (49) and several derivatives has been reported (147). [Pg.123]

Oxetanocin oxetanocinA, 9-[(2/ ,3/ ,45)-3,4-bis-(hydroxymethyl)-2-oxetanyl]adenine. CioHijNgOj, Mr 251.24, needles (XH2O), mp. 197 °C, [a]g> -44.3° (pyridine), a nucleoside antibiotic from culture broths of Bacillus megaterium exhibiting antibacterial and potent antiviral activities. In the name O. A the A is in-... [Pg.458]

Oxetanocin A is an antibiotic isolated in 1986 from culture filtrate of Bacillus megaterium strain NK84-0228 [201], The structure, on the basis of spectroscopic data as well as X-ray crystallographic analysis, was determined to be 9-[27 ,3R,45)-3,4-bis(hydroxymethyl)-2-oxetanyl]adenine (Figure 4.40) [202]. [Pg.341]

See other pages where Oxetanocin from Bacillus megaterium is mentioned: [Pg.401]    [Pg.102]    [Pg.213]    [Pg.353]    [Pg.967]    [Pg.87]    [Pg.341]   
See also in sourсe #XX -- [ Pg.10 , Pg.585 ]



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Bacillus megaterium

Oxetanocins

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