B-cell transcription factors

Matsen, S. and Shiverick, K., The Ah receptor recognizes DNA binding sites for the B cell transcription factor BSAP A possible mechanism for dioxin-mediated alteration of CD 19 gene expression in human B lymphocytes, Biochem. Biophys. Res. Comm., 212, 27, 1995. 

Browne P, Petrosyan K, Hernandez A, et al. The B-cell transcription factors BSAP, Oct-2, and BOB.l and the pan-B-cell markers GD20, GD22, and GD79a are useful in the differential diagnosis of classic Hodgkin lymphoma. Am J Clin Pathol. 2003 120 767-777. 

TABLE 6.1 B-Cell Transcription Factors Common Expression Patterns ... 

Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, Chiao PJ. 1999. The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 5 119-127. 

Flanagan WM, Corthesy B, Bram RJ, Crabtree GR, Nuclear association of a T-cell transcription factor blocked by FK506 and cyclosporin A, Nature 1992 352 803-807. 

Figure 10.24 Structure of a monomer of the DNA-binding domain of the transcription factor MyoD. The domain, which belongs to the b/HLH family, comprises two a helices joined by a loop region. The basic region (blue) and the first helix HI (red) of the helix-loop-helLx region form one continous a helix. (Adapted from P.C.M. Ma et al.. Cell 77 451-459, 1994.)...

Family of transcription factors that modulate the expression of genes which control immune, inflammatory, and acute-phase responses, as well as cell growth, responses to stress, apoptosis, and oncogenesis. All members of this family have a Rel-homology domain that contains sequences responsible for dimerization and DNA binding. In vertebrates, this family includes NF-kB1 (also known as p50), NF-kB2 (also known as p52), Rel (also known as cRel), Rel-A (also known as p65), and Rel-B. 

Abravaya, K., Phillips, B., Morimoto, R.I. (1991a). Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures. Genes and Dev. 5, 2117-2127. 

Gamer, J., Bujard, H., Bukua, B. (1992). Physical interaction between heat shock proteins DnaK, DnaJ, CJtpE the bacterial heat shock transcription factor sigma 32. Cell 69, 833-842. 

Mosser, D.D., Duchaine, J., Massie, B. (1993). The DNA binding activity of the human heat shock transcription factor is regulated in vivo by hsp70. Mol. Cell. Biol. 13, 5427-5438. 

Keaveney M, Struhl K Activator-mediated recruitment of the RNA polymerase machinery is the predominant mechanism for transcriptional activation in yeast. Mol Cell 1998 1 917. Lemon B, Tjian R Orchestrated response a symphony of transcription factors for gene control. Genes Dev 2000 l4 255l. Maniatis T, Reed R An extensive network of coupling among gene expression machines. Nature 2002 416 499. 

Roy S, Cain KJ, Chapin RB, Charboneau RG, Barke RA (1998) Morphine modulates NF kappa B activation in macrophages. Biochem Biophys Res Commun 245 392-396 Roy S, Wang J, Gupta S, Charboneau R, Loh HH, Barke RA (2004) Chronic morphine treatment differentiates T helper cells to Th2 effector cells by modulating transcription factors GATA 3 and T-bet. J Neuroimmunol 147 78-81... 

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