Atropen

Immediate treatment of an exposed individual is essential. The U.S. regimen includes the pretreatment, and after exposure atropine and 2-PAM are self-adininistered. Eurther treatment includes up to two additional doses, followed by the tranquilizer VaHum. As required, artificial respiration is instituted, clearing the airway if necessary. The current standard U.S. Army atropine item is the automatic injector, Atropen, designed for self-adininistration by the individual in the field. 

No more than 3 AtroPen injections should be used unless the patient is under the supervision of a trained medical provider. Different dose strengths of the AtroPen are available depending on the recipient s age and weight. 

Children weighing less than 15 lbs (generally younger than 6 months of age) should ordinarily not be treated with the AtroPen auto-injector. Atropine doses for these children should be individualized at doses of 0.05 mg/kg. 

Brand Name(s) AtroPen Autoinjector, Atropine Care, Atropisol, Atrosulf-1, Isopto Atropine, Ocu-Tropine, Sal-Tropine Cfiemical Class Belladonna alkaloid... 

Acetylcysteine (Aceta-dote, Mucomyst) Albuterol (Proventil, Ventolin, Volmax) Amifostine (Ethyol) Atropine (AtroPen) Atropine/Pralidoxime (DuoDote)... 

Autoinjectors (AtroPen , Mark I , Combopen MC ) are atropine or atropine and pralidoxime combinations available for human use. They are not used in veterinary medicine as they are not adjustable for different sized patients. Experimental vaccines against nerve agent VX, and monoclonal antibodies which protect against soman, sarin, and tabun toxicity have been produced and are being tested (Dunn and Sidell, 1989 Somani et al, 1992). 

These products are provided by Meridian Medical Technologies, which has partnered with the US Department of Defense to be the only FDA-approved supplier of nerve agent antidotes. The Mark I kit and the single autoinjector devices deliver 600 mg of 2-PAM Cl and 2 mg of atropine (AtroPen ) in seconds. This kit was developed originally... 

FIGURE 61.6. The Atropen pediatric autoinjectors. Dose sizes 0.25 mg - infant, 0.5 mg - child (7-18 kg), 1 mg - child (18 1 kg), 2 mg - adolescent/adults. Photograph reproduced with permission from Meridian Medical Technologies . 

FIGURE 61.7. Technique for using Atropen pediatric autoinjector. 

Synonyms AtroPen auto injector Atropine sulfate injection Atropisol Atrosulf-1 Ocu-tropine Ocean-A/S Sal-tropine... 

Zusammenfassend kann man feststellen, dafi die / -substituierten Paraffine sich ebenso wie die atropen Diphenyle in chemischer und physikalischer Beziehung wie, verdoppelte Monoradikale verhalten, demnach als Biradikale im eigentlichen Sinne vorliegen. 

Von der Stoffklasse der atropen Biradikale war bisher nur der Typus besprochen, der durch eine tnaximale Verdrehtmg dei beiden... 

Tabelle 16. Valemformeln und Mesomerieenergie bei einem atropen Biradikal, dem ScHLENKsc ew Biradikalett und dem Biradikaloid von Tschitschibabin. 

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