Atomic force microscopy high-resolution

During investigations we were analyzing samples by methods of X-ray diffraction, electron scanning microscopy, microprobe analysis, atomic force microscopy, high-resolution transmission electron microscopy with preliminary attracting of the another methods including optical microscopy, Raman spectroscopy, thermal analysis and some of others. 

Gullo, M. R., P. Frederix, T. Akiyama, A. Engel, N. F. deRooij, and U. Staufer, Characterization of microfabricated probes for combined atomic force and high-resolution scanning electrochemical microscopy, Anal. Chem., Vol. 78, 2006 pp. 5436-5442. 

Shao Z and Yang J 1995 Progress in high-resolution atomic-force microscopy in biology Qt Rev. Biophys. 28 195 Shao Z, Mou J, Cza]kowsky D M, Yang J and Yuan J 1996 Biological atomic force microscopy what is achieved and... 

Atomic force microscopy (AFM) has become a standard technique for high-resolution imaging of the topography of surfaces. It enables one to see nanoscopic... 

The FFM based on the atomic force microscopy (AFM) is the most available tool to study the feature of microscale friction and wear of material surface with high resolution [6]. So the... 

The combination of atomic force microscopy (AFM) and Raman spectroscopy is another approach to attain high spatial resolution. AFM also employs a sharp tip close to a sample surface. When the tip is made of metal and light is irradiated onto the tip and surface, Raman scattering is largely enhanced. In this way, a spatial resolution of 15 nm is achieved [2]. 

High-Resolution scanning electron and atomic force microscopies observation of nanometer features on zeolite Surfaces... 

It is now possible to observe nanometer features on the surfaces of zeolitic materials using high-resolution scanning electron microscopy. By taking ibidem measurements in combination with atomic force microscopy we are able to illustrate the strengths and weaknesses of both techniques and judge respective resolving power. 

Atomic force microscopy (AFM) can be used to obtain high-resolution imagery of molecular orientation and ordering for materials adsorbed onto substrates. Early AFM studies on gluconamides were hampered by the tendency of the fibers to unravel on substrates forming bilayer sheets.41 These layers showed the head-to-tail packing of a monolayer which is similar to the crystal structure reported for anhydrous gluconamides.38 A procedure to retain the fiber networks on surfaces with the addition of a small fraction of... 

Han W, Mou J, Sheng J, Yang J, Shao Z. Cryo atomic force microscopy A new approach for biological imaging at high resolution. Biochemistry 1995 34 8215-8220. 

Shao Z, Yang J. Progress in high resolution atomic force microscopy in biology. Quarterly Rev Biophysics 1995 28 195-251. 

Baldwin PM, Adler J, Davies MC, Melia CD. High resolution imaging of starch granule surfaces by atomic force microscopy. J Cereal Sci 1998 27 255-265. 

Baker AA, Helbert W. Sugiyama J, Miles MJ. High-resolution atomic force microscopy of native Valonia cellulose I. Microcrystals. J Struct Biol 1997 119 129-138. 

Huff, M. E., Balch, W. E., and Kelly, J. W. (2003). Pathological and functional amyloid formation orchestrated by the secretory pathway. Curr. Opin. Struct. Biol. 13, 674-682. Jansen, R., Dzwolak, W., and Winter, R. (2005). Amyloidogenic self-assembly of insulin aggregates probed by high resolution atomic force microscopy. Biophys. J. 88, 1344-1353. 

Among the many microscopy-based techniques for the study of biomolecular interactions on surfaces, scanning probe microscopies, and especially the atomic force microscopies (AFM), are the most used because of their molecular and sub-molecular level resolution and in situ imaging capability. Apart from the high resolution mapping of siuface nanotopographies, AFM can be used for the quantification and visualisation of the distribution of chemistry, hydrophobicity and local mechanical properties on surfaces, and for the fabrication of nanostructmes on surfaces. 

Figure 10.5 High resolution Atomic Force Microscopy image of plasmid DNA adsorbed on a cationic bilayer (DPTAP) coating a freshly cleaved mica surface. The highly packed DNA chains are clearly visible. The measured width of DNA is 2nm, close to the diameter of B-DNA (Adapted fromMou etal., 1995 Fang and Yang, 1997).

Mou, J., Czajkowsky, D.M., Zhang, Y. and Shao, Z. (1995) High-resolution atomic-force microscopy of DNA the pitch of the double helix. FEES Lett., 371, 279-282. 

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