Artemisia arborescens

Fattorusso, C. Stendardo, E. Appendino, G. Fattorusso, E. Luciano, P. Romano, A. Taglialatela-Scafati, O. Artarborol, a nor-caryophyllane sesquiterpene alcohol from artemisia arborescens. Stereostructure assignment through concurrence of NMR data and computational analysis, Org. Lett. 2007, 9, 2377-2380. 

Arborescin (586), a metabolite of Artemisia arborescens, has been synthesized (Scheme 59) from the eudesmanolide derivative (421) previously used in the synthesis of vulgarin " cf. p. 128). 

CijHjflOs, Mr 248.32, cryst., mp. 140-142 °C, [aj -1-64° (CHCI3) soluble in acetone and DMF. A sesquiterpene lactone from Artemisia arborescens (Astera-... 

The antiviral activity of the oil obtained from Artemisia arborescens L was also studied by Sinico et al. (2005). They studied the influence of vesicle structure and composition on the antiviral activity, against herpes simplex virus type 1 (HSV-1), of the vesicle-incorporated oil, multilamellar vesicles (MLV), and small unilamellar vesicles (SUV) positively charged liposomes prepared by the film method and sonication. The liposomal incorporation of A. arborescens EO enhanced the in vitro antiherpetic activity mainly when vesicles were made with hydrogenated soy phosphatidylcholine. 

Ornano, L., A. Vendittin, M. Ballero et al., 2013. Chemopreventive and antioxidant activity of the chamazu-lene-rich essential oils obtained from Artemisia arborescens L. growing on the Isle of La Maddalena,... 

Sinico C, De Logu A, LaiF, Valenti D, Manconi M, Loy G, Bonsignore L, Fadda AM (2005) Liposomal incorporation of Artemisia arborescens L. essential oil and in vitro antiviral activity. Eur J Pharm Biopharm 59 161... 

Lai F, Wissing SA, Muller RH, Fadda AM (2006) Artemisia arborescens L essential oil-loaded solid lipid nanoparticles for potential agricultural application preparation and characterization. AAPS Pharm Sci Technol 7 E2... 

Isol. from roots of Artemisia arborescens and Liatris pycnostachya. Cryst. (pet. ether). Mp 100.5° (92-94°). 

The Artemisia arborescens L. essential oil showed significant antiviral activity against Herpes simplex virus type 1 (HSV-1) (Sinico et al. 2(X)5). Peppermint oil, the essential oil of Mentha piperita, exhibited high levels of virucidal activity against HSV-1 and HSV-2, and it is also active against an acyclovir resistant strain of HSV-1 (HSV-1-ACV" ) (Schuhmacher et al. 2003). 

Artemisia arborescens yields about 0-6 per cent, of a deep blue essential oil of specific gravity about 0-946, acid value 9 8, and ester value 19 5. According to Jona it contains 13 9 per cent, of alcohols, of which borneol and thujyl alcohol have been identified, and about 13 per cent, of thujone. As constituents of the esters there were found formic, acetic, isovalerianic, pelargonic, palmitic, and stearic acids. 

Artemisia arborescens L. essential oil Camphor pThujone Chamazulene alginate bead antiviral [22]... 

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