Apomorphine stereotyped behaviors induced

Szechtman H, Ornstein K, Teitelbaum P, Golani I (1985) The morphogenesis of stereotyped behavior induced by the dopamine receptor agonist apomorphine in the laboratory rat. Neuroscience 74 783-798. 

Asakura W., Matsumoto K, Ohta H., Watanabe H. (1992). REM sleep deprivation decreases apomorphine-induced stimulation of locomotor activity but not stereotyped behavior in mice. Gen. Pharmacol 23, 337-41. 

Inhibition of conditioned (but not unconditioned) avoidance behavior is one of the most predictive tests of antipsychotic action. Another is the inhibition of amphetamine- or apomorphine-induced stereotyped behavior. Other tests that may predict antipsychotic action are reduction of exploratory behavior without undue sedation, induction of a cataleptic state, inhibition of intracranial self-stimulation of reward areas, and prevention of apomorphine-induced vomiting. Most of these tests are difficult to relate to any model of clinical psychosis. 

Lipska BK, Weinberger DR. 1993. Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat. Brain Res Dev Brain Res 75 213-222. 

Several lines of evidence show that dopamine (DA) is implicated in the mediation of some obsessive-compulsive behavior. Animal studies demonstrate that high doses of various dopaminergic agents, such as amphetamine, bromocriptine, apomorphine, and L-DOPA, induce stereotyped movements in animals, which resemble compulsive behaviors in OCD patients. Increased dopaminergic neurotransmission may be responsible for this. Human studies consistently report that abuse of stimulants such... 

Magaji et al. showed in 2008 that the cmde methanol root-bark extract of Flueggea virosa possessed antidopaminergic activity. More recently, the extract of the same plant was evaluated on two murine experimental models, apomorphine-induced stereotypic climbing behavior and swim-induced... 

Riffee WH, Wilcox RE, Smith RV, Davis PJ, Brubaker A (1982) Inhibition of R(-)-apomorphine-induced stereotypic cage-climbing behavior in mice by S(+)-apomorphine. Adv Biosci 37 357-362... 

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