Aphthous ulcers, oral cavity

Aphthous ulcer A small superficial area of ulceration within the gastrointestinal mucosa, typically found in the oral cavity. 

Ulcerating lesions Topical treatment of ulcerating lesions of the oral cavity, such as recurrent aphthous stomatitis (canker sores). 

Localized dmg delivery to the mouth is used for the treatment of conditions of the oral cavity, principally aphthous ulcers, fungal conditions and periodontal disease. However, in addition to topical delivery, there has been considerable interest in the possibility of oral transmucosal delivery in order to achieve the... 

The oral cavity is lined with delicate mucus membranes that allow rapid absorption of harmful chemicals present in food, drinks, tobacco products and dental materials across its surface. The oral tissues are also vulnerable to cell damage through trauma, bacterial onslaught and other disease-causing agents. The oral cavity is therefore uniquely susceptible to oxidative stress that can be responsible for a number of oral diseases such as periodontitis [6], aphthous ulcers [14], lichen planus [15,13] and oral submucous fibrosis [16], some of which may develop into oral cancers [15,17]. 

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