Anxiety impairment

Anxiety is a normal part of mental life and plays a crucial role in human psychological development and other forms of learning. Although systematic studies are lacking, suppression of normal levels of anxiety could impair the development of adaptive coping mechanisms. On the other hand, disabling anxiety impairs adaptation as well and is associated with significant morbidity and mortality. 

Neuropsychiatric Depression, anxiety, impaired mental cognition. 

Smith GW, Aubry J-M, Dellu F, Contarino A, BUezikijan LM, Gold LH, Chen R, Marchuk Y, Flauser C, Bentley CA, Sawchenko PE, Koob GF, Vale WW, Lee KF (1998) Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 20 1093-1102... 

Impaired regulation of affective state and anxiety Impaired social behavior and sensitivity Impaired cognitive processing No diagnosis of autism... 

A review has summarized the evidence related to the adverse effects of acute and chronic use of cannabis (60). The effects of acute usage include anxiety, impaired attention, and increased risk of psychotic symptoms. Probable risks of chronic cannabis consumption include bronchitis and subtle impairments of attention and memory. 

Musculoskeletal Cramping and muscle pain. Neuropsychiatric Depression, anxiety, impaired mental cognition, fatigue, and sexual dysfunction. 

Depression is one of the most common psychiatric disorders. It is characterized by feeling of intense sadness, helplessness, worthlessness, and impaired functioning. Those experiencing a major depressive episode exhibit physical and psychological symptoms, such as appetite disturbances, sleep disturbances, and loss of interest in job, family, and other activities usually enjoyed. A major depressive episode is a depressed or dysphoric (extreme or exaggerated sadness, anxiety, or unhappiness) mood that interferes with daily functioning and includes five or more of the symptoms listed in Display 31-1. 

P = Psychological symptoms (anxiety, psychosis, cognitive impairment, depression)... 

Initially, most prominent effect is elated mood, although depression may occur hypervigilance and anxiety that may progress to panic with high doses or chronic use, may see impairment of judgment, violence to others or self, paranoia or psychosis with delusions and hallucinations (hallucinations are generally tactile or auditory, rarely visual) an increase in motor activity is common compulsive or stereotyped behavior (e.g., skin picking) may be seen severe intoxication may result in a self-limited delirium... 

Assess the patient s symptoms and level of functional impairment to determine if pharmacotherapy is appropriate for the anxiety disorder. 

Lung Fever, impaired gas exchange, SOB, malaise, anxiety Decreased FEV, infiltrate on CXR, biopsy positive for lymphocytic infiltration... 

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