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Antineoplastic drugs alkaloids

Veno-occlusive disease (VOD) differs from Budd-Chiari syndrome in that it consists of occlusive fibrosis of the small intrahepatic veins. VOD may present as either an acute form with sudden ascites, liver enlargement and rapidly rising bilirubin, or as a chronic form with fibrosis and cirrhosis. One of the main causes of VOD is the use of cyclophosphamide or alkalating agents during conditioning for bone marrow transplantation, where it occurs in up to 20% of cases. Other causes include irradiation, antineoplastic drugs, pyrrolizidine alkaloids and alcohol. [Pg.68]

Many other alkaloid-based medicines exist. Drugs based on berberine are used in the treatment of infections as well as in the treatment of AIDS. The taxanes (e.g., paclitaxel in Taxol drug and its synthetic analogue, docetaxel in Taxotere) have antineoplastic agents to cure cancers, Kaposi s sarcoma, and squamous cell carcinomas. Several novel alkaloids and their synthetic analogues are under development and considered to being accepted by U.S. Food and Drug Administration for clinical use. ... [Pg.369]

See other pages where Antineoplastic drugs alkaloids is mentioned: [Pg.85]    [Pg.568]    [Pg.586]    [Pg.34]    [Pg.85]    [Pg.649]    [Pg.243]    [Pg.551]    [Pg.226]    [Pg.571]    [Pg.26]    [Pg.27]    [Pg.40]    [Pg.353]    [Pg.780]    [Pg.3]    [Pg.483]    [Pg.2290]    [Pg.2323]    [Pg.837]    [Pg.79]    [Pg.1011]    [Pg.780]    [Pg.853]    [Pg.385]    [Pg.242]    [Pg.254]    [Pg.340]   
See also in sourсe #XX -- [ Pg.36 , Pg.38 , Pg.50 ]



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