Antifungal activity, plant

Flores, T, Alape-Giron, A., Flores-Diaz, M., Flores, H.E. Ocatin. A novel tuber storage protein from the Andean tuber crop oca with antibacterial and antifungal activities. Plant Physiol. 2002, 128, 1291-1302... 

Altemarla solani, removal of monosaccharide units of glycoalkaloids, 297,299 Ambrosia psllostachya. production of sesquiterpene lactones, 104 Antifungal activity, plant steroids, 286-301... 

Although the antibacterial and antifungal activities of bialaphos and phosphinothricin were not found to be usehil, the two agents were later used as biodegradeable, relatively nonselective, postemergent herbicides. Glutamine synthetase inhibition is toxic to plants because the enzyme is key to ammonia assimilation. There is some selectivity for individual plant species as shown by the LD for bialaphos ranging from 0.125 to 8.5 kg/ha (301—303). 

Hindi karipatta) tree (Fig. 1). The leaves of this small tree are used as a spice for the preparation of curry. Extracts from various parts of the plant have a strong antibacterial and antifungal activity and therefore are applied in folk medicine [12]. 

Lipid transfer peptides and proteins occur in eukaryotic and prokaryotic cells. In vitro they possess the ability to transfer phospholipids between lipid membranes. Plant lipid transfer peptides are unspecific in their substrate selectivity. They bind phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, and glycolipids. Some of these peptides have shown antifungal activity in vitro The sequences of lipid transfer proteins and peptides contain 91-95 amino acids, are basic, and have eight cysteine residues forming four disulfide bonds. They do not contain tryptophan residues. About 40% of the sequence adopts a helical structure with helices linked via disulfide bonds. The tertiary structure comprises four a-helices. The three-dimensional structure of a lipid transfer peptide from H. vulgare in complex with palmitate has been solved by NMR. In this structure the fatty acid is caged in a hydrophobic cavity formed by the helices. 

Furanocoumarins from Ruta graveolens possess antifungal activity to several plant pathogenic fungi. 7-Hydroxycoumarin, 4-hydroxycoumarin, and 7-methoxycoumarin were active against Colletotrichum species that cause Anthracnose disease of strawberry. 

Antifungal activity. Ethanol (50%) extract of the entire plant, in broth culture at a concentration of 1 mg/mL, was inactive on Aspergillus fumigatus and Trichophyton men tagrophytes Hot water extract of the leaf on agar plate at a concentration of 1.0% was active on Altemaria tenuis, Pythium aphu ... 

Antifungal activity of plant extracts used in therapy. 11. Study of a 40 plant DC224 extracts against 9 fungi species. Ann PharmFr 1985 43(1) 77-81. 

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