Anti-nerve growth factor

Capsoni, S., Giannotta, S., and Cattaneo, A., Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice, Proc. Natl. Acad. Sci. U.S.A., 99, 12432, 2002. 

Seeley, P.J., Keith, C.H., Shelanski, M.L. and Greene. L.A. (1983) Pressure microinjection of nerve growth factor and anti-nerve growth factor into the nucleus and cytoplasm lack of effects on neurite outgrowth from pheochromocy-toma cells. J. Neurosci. 3 1488-1494. 

Sanga P, Katz N, Polverejan E, Wang S, Kelly KM, Haeussler J, et al. Efficacy, safety, and tolerability of fulranumab, an anti-nerve growth factor antibody, in the treatment of patients with moderate to severe osteoarthritis pain. Pain 2013 154(10) 1910-9. 

Mouse nerve-growth factor Isolation of sheep anti-(nerve-growth factor) antibodies 73... 

Figure 2.8. Scheme of a chimeric peptide with examples for each of the distinct domains. 0X26, anti-rat transferrin receptor monoclonal antibody (mAh) 84-15, anti-human insulin receptor mAh cHSA, cationized human serum albumin VIP, vasoactive intestinal polypeptide DALDA, dermorphin analogue NGF, nerve growth factor BDNF, brain-derived neurotrophic factor PNA, peptide nucleic acid (3-gal, (3-galactosidase. 

A recent study by Brunner a al. (1993) has confirmed that mature human basophUs synthesize and release IL-4. For optimal secretion, priming with IL-3 for 18-48 h before activation with anti-IgE was required, although low amounts of IL-4 were occasionally detected following incubation with either IL-3 or anti-IgE alone. No spontaneous IL-4 production was detected, and other cytokines known to enhance basophil mediator release, namely IL-5, GM-CSF and nerve growth factor (NGF),... 

Melamed I, Franklin RA, Gelfand EW (1995a) Microfilament assembly is required for anti-IgM dependent MAPK and p90rsk activation in human B lymphocytes. In Biochem and Biophys Res Comm. 209 1102-10 Melamed I, Stein L, Roifman CM (1994) Epstein-Barr virus induces actin polymerization in human B cells. In J Immunol. 153 1998-2003 Melamed I, Turner CE, Aktories K, et al. (1995b) Nerve growth factor triggers microfilament assembly and paxillin phosphorylation in human B lymphocytes. In J Exp Med. 181 1071-9... 

De Rosa, R., Garcia, A.A., Braschi, C., Capsoni, S., Maffei, L., Berardi, N. and Cattaneo, A. (2005) Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD 11 anti-NGF... 

The epitopes recognized by Hawkes family of monoclonal antibodies known as the anti-Zebrins are localized on Purkinje cells (see Section 3.1.8.). Zonal patterns that are identical or very similar to Zebrin I and II have been described for the distribution of 5 -nucleotidase (see above), the p75 low affinity nerve growth factor receptor protein in the rat (Section 3.1.10., Fig. 38), protein kinase C delta (Fig. 133) (see Section 3.1.5.) and the B30 antibody of Stainier and Gilbert (1989) (see Section 3.1.8.). Immunoreactiv-ity in mouse Purkinje cells for an antibody against HNK is partially congruent with the Zebrin negative Purkinje cells, but Zebrin+/HNK-l- Purkinje cells also exist (Hawkes, 1992 Eisenman and Hawkes, 1993). The similarity between the Zebrin pattern and the transient zonal patterns in the development of the Purkinje cell specific marker L7 is discussed in Section 6.2. 

El Yazidi-Belkoura 1., Adriaenssens E., Dolle L., Descamps S., Hondermarck H., 2003, Tumor Necrosis Factor Receptor-Associated Death Domain Protein (TRADD) is Involved in the Neurotrophin Receptor (p75NTR)-Mediated Anti-Apoptotic Activity of Nerve Growth Factor in Breast Cancer Cells. J.5io/.C/ em. 278 16952-16956. 

In addition, PPARy agonists prevent Ap-induced neurodegeneration in hippocampal neurons, and PPARy is activated by the nerve growth factor (NGF) survival pathway, suggesting a neuroprotective anti-inflammatory independent action (Fuenzalida et al., 2007). It is shown that PPARy agonist rosiglitazone... 

Generic Names nerve growth factor antibodies (anti-NGF)... 

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