Anti-emetic drugs

Mendelson s syndrome Cytoprotectants Mucosal protective drugs Prokinetic and anti-spasmodic drugs Laxatives Anti-diarrhoeals Nausea and vomiting Pharmacology of anti-emetic drugs Other substances Non-pharmalogical therapy INTRODUCTION... 

Metoclopramide and domperidone are discussed below in the section on anti-emetic drugs. 

Table 11.2 Receptor site affinity of anti-emetic drugs (modified from Peroutka and Snyder 1982 Hamik and Peroutka 1989)...

Chiorphenamine is effective in reducing pruritus from opioid drugs and may have synergistic activity with other anti-emetic drugs, although it is not primarily used as an anti-emetic. 

Ackermann, B. L. Gillespie, T. A. Regg, B. T. Austin, K. E Coutant, J. E. 1996b. Application of packed capillary liquid chromatography/mass spectrometry with electrospray ionization to the study of the human biotransformation of the anti-emetic drug dolasetron. /. Mass Spectrom., 37,681-689. 

The nitro compound below was needed for the synthesis of an anti-emetic drug. It was proposed to make it by nitration of the hydrocarbon shown. How successful do you think this would be ... 

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