Aneurysms, formation

Copper is an essential component of numerous key metalloenzymes which are critical in melanin formation, myelin formation and crosslinking of collagen and elastin. Copper plays a vital role in hemopoiesis, maintenance of vascular and skeletal integrity, and structure and function of the nervous system. Thus a deficiency of copper can lead to a variety of adverse effects such as increased fragility in bones, aneurysm formation in arteries and a loss of lysyl oxidase activity in cartilage.54 57 Articles on copper also appear in Siget1, volumes 3 and 5, all of volumes 12 and 13, and volume 14,... 

Carotid loops may be associated with aneurysm formation and rarely with embolism, endothelial damage and thrombosis exceptionally there may be focal ischemia on head movement (Sarkari et al. 1970 Desai and Toole 1975). Rarely, these loops may cause hypoglossal nerve lesions or pulsatile tinnitus. 

Some inherited disorders of connective tissue (Table 3.2) can present with, or be complicated by, arterial dissection or even rupture, intra- and extracranial aneurysm formation. 

Origuchi N, Komiyama T, Ohyama K, Wakabayashi T, Shigematsu H. Infectious aneurysm formation after depot acupuncture. Eur J Vase Endovasc Surg 2000 20(2) 211-13. 

Greatorex J C 1977 Diagnosis and treatment of verminous aneurysm formation in the horse. Veterinary Record 101 184-187... 

Carmehet, R, et al.. Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation. Nat Genet, 1997. 17(4) p. 439-44. 

MMPs have been implicated in the pathogenesis of aneurysm formation. Plasma MMP-9 levels have been reported to be elevated in patients with abdominal aortic aneurysms (86 12 ng/ml) as compared to patients with symptomatic aortic occlusive disease (26 4 ng/ml) or with healthy volunteers (13 2 ng/ml) (MIO). Patients with multiple aneurysms have... 

Progression of disease Transition from hypertrophy to failure Ventricular dilation Infarct expansion Response to reperfusion Aneurysm formation... 

Gupta, K.B., Ratcliff, M.B., Fallert, M.A. et al.. Changes in passive mechanical stiffness of myocardial tissue with aneurysm formation. Circulation, 89, 2315-2326,1994. 

Figure 2.3 Bovine heterograft with aneurysm formation (arrows) following implantation for...

Bounce AH. Aneurysm formation in human umbdical vein grafts used as arterial substitutes. JVasc Surg 1985 2 524-9. 

Giordano JM, Keshishian JM. Aneurysm formation in human umbilical vein grafts. Surgery 1982 91 343-5. 

An important further development of the retrieval study would be the simulation and modeling of in vivo performance of the biotextile implant. By simulating the various parameters such as blood flow and tissue-material interactions it may in the future be possible to predict such biological response variables as thrombosis, aneurysm formation and the rate of healing. 

Inflammatory transmural angiitis in systemic lupus erythematosus, polyarteritis nodosa, or giant cell arteritis causes focal fibrinoid necrosis and elastic tissue disruption. Subacute or chronic changes usually produce ectasia and may facilitate aneurysm formation. Aneurysms in acute arteritis tend to be multiple, peripheral and non side-wall in configuration. 

Cardiac myxoma may be a very rare cause of SAH. In exceptional cases it may metastasize into an intracranial artery, infiltrate the vessel wall and initiate aneurysm formation, even more than 1 year after excision of the primary tumour (Furuya et al. 1995). 

Taylor CL, Yuan Z, Selman WR, Ratcheson RA, Rimm AA (1995) Cerebral arterial aneurysm formation and rupture in 20,767 elderly patients hypertension and other risk factors. J Neurosurg 83 812-819 Teunissen LL, Rinkel GJ, Algra A, van Gijn J (1996) Risk factors for subarachnoid hemorrhage a systematic review. Stroke 27 544-549... 

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