Anesthetics confusion caused

Overexposure to tetrachloroethylene by inhalation affects the central nervous system and the Hver. Dizziness, headache, confusion, nausea, and eye and mucous tissue irritation occur during prolonged exposure to vapor concentrations of 200 ppm (15). These effects are intensified and include incoordination and dmnkenness at concentrations in excess of 600 ppm. At concentrations in excess of 1000 ppm the anesthetic and respiratory depression effects can cause unconsciousness and death. A single, brief exposure to concentrations above 6000 ppm can be immediately dangerous to life. Reversible changes to the Hver have been reported foUowing prolonged exposures to concentrations in excess of 200 ppm (16—22). Alcohol consumed before or after exposure may increase adverse effects. 

Lighter fuels, benzene, toluene, cleaning fluids (carbon tetrachloride), petrol, paraffin, and even the fluorocarbon propellants found in various household sprays and medications have all been used, particularly by children, to produce changes in consciousness. They are all inhaled, often with the aid of a plastic bag, and, since they are lipid-soluble, they are readily concentrated in brain tissue. As with many anesthetics there is an early period of hyperactivity, excitement, and intoxication, followed by sedation and confusion. Prolonged or regular use can cause serious toxicity, with bone-marrow depression, cardiac dysrhythmias, peripheral neuropathy, cerebral damage, and liver and kidney disorders (1). 

Central nervous system effects of low concentrations of local anesthetics are mainly sedation and confusion high concentrations are more likely to cause seizures (18). 

Cyclohexane is a CNS depressant and may produce mild anesthetic effects. Inhalation exposure can cause headache, nausea, dizziness, drowsiness, and confusion. Very high concentrations may cause unconsciousness, convulsions, and death. Vapors may be irritating to the nose and throat. Severe lung irritation, damage to lung tissues, or death may result from aspiration into the lungs. Direct dermal contact with liquid may cause mild irritation, which may... 

Phencyclidine and its derivatives are analogs of ketamine, which is used therapeutically as an anesthetic. Phencyclidine itself, until the late 1970s, was indicated for this use in the field of veterinary medicine, as in 1965 its use in human medicine had been discontinued because it caused states of excitation and confusion. The symptoms caused by abuse are strongly dependent on the dose, ranging from feelings of euphoria and floating to paranoid states of... 

Corrosive. Skin and eye contact can cause severe burns. Exposure may be proionged owing to local anesthetic action on skin. Weii absorbed by aii routes. Dermal absorption is a major route of systemic poisoning, induces methemoglobinemia (see p 261). CNS depressant. Symptoms include headache, nausea and vomiting, tinnitus, dizziness, weakness, and confusion. Severe lung, liver, and kidney injury may occur. See also phenol, p 302. S (ortho) 3 2 0 (mela, parti) odor. Vapor pressure is 0.2 mm Hg at 20°C (68°F). Combusbble. 

MC is an anesthetic. Inhaling the vapor may cause mental confusion, light-headedness, nausea, vomiting, and headache. Continued exposure may cause increased light-headedness, staggering, unconsciousness, and even death. High vapor concentrations may also cause irritation of the eyes and respiratory tract. Exposure to MC may make the symptoms of angina (chest pains) worse. 

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