And methyl bis-

Benzamide (121 mg, 1.0 mmol) and methyl bis(l-naphthyl)bismuthinate (510 mg, 1.0 mmol) were stirred in a mixture of acetic acid (5 ml) and dichloromethane (20 ml) at room temperature. When the starting amide was consumed completely, the mixture was evaporated to dryness in vacuo and the residue was passed through a silica gel column using hexane-dichloromethane (100% hexane to 100% dichloromethane) as the eluent. Al-Acetylbenzamide was obtained in 89% isolated yield [90CL1651]. 

HN3]) to moderately persistent (ethyl bis [2-chloroethyl] amine [HN1] and methyl bis[2-chloroethyl]amine [HN2]). The nitrogen mustards break down into water-soluble, less toxic compounds. Cyanogen chloride (agent... 

Polyurethane from butane diol, phenylphosphonic dichloiide, and methylene bis-(4-phenyl isocyanate) Polyester urethane from an ethylene/ propylene glycol/adipic acid polyester, butane diol and methyl bis-(4-phenyl isocyanate)... 

The solution in A is now treated with mercuric chloride and methyl-red, and then titrated with Ml 10 HCl until its colour matches that of the solution in B. The difference in the volume of HCl run in from the burettes A and Bi is a measure of the amount of urea present. 

Examples of photothermoplasts include polyacrylates, polyacrylamides, polystyrenes, polycarbonates, and their copolymers (169). An especially well-re searched photothermoplast is poly(methyl methacrylate) (PMMA), which is blended with methyl methacrylate (MMA) or styrene as a monomer, and titanium-bis(cyclopentadienyl) as a photoinitiator (170). 

N,]S7-bis(methoxymethyl)uron was first isolated and described in 1936 (41), but was commercialized only in 1960. It is manufactured (42) by the reaction of 4 mol of formaldehyde with 1 mol of urea at 60°C under highly alkaline conditions to form tetramethylolurea [2787-01-1]. After concentration under reduced pressure to remove water, excess methanol is charged and the reaction continued under acidic conditions at ambient temperatures to close the ring and methylate the hydroxymethyl groups. After filtration to remove the precipitated salts, the methanolic solution is concentrated to recover excess methanol. The product (75—85% pure) is then mixed with a methylated melamine—formaldehyde resin to reduce fabric strength losses in the presence of chlorine, and diluted with water to 50—75% soHds. Uron resins do not find significant use today due to the greater amounts of formaldehyde released from fabric treated with these resins. 

The 2- and 4-alkylthioquinazolines are formed by the second or third of the above methods as appropriate. For example, quinazoline-2(l//)-thione and methyl iodide/alkali give the thioether (883) and the 4-thioether is made similarly (62JCS3129) 2,4-dichloroquinazoline and sodium p-chlorothiophenate give 2-chloro-4-p-chlorophenylthio-(884 R = C1) or 2,4-bis-p-chlorophenylthio-quinazoline (884 R = SC6H4C1) according to conditions (48JCS1766). 

This series of compounds was also discussed briefly by Quilico in 1962 and only a limited number of new representatives have been reported 62HC(17)l,p. 3). The pressure reaction of ethylene and nitric acid in the presence of Ni, Zn or Cu produced 3,3 -bis(isoxazoline) 70FRP94493), and the isoxazoline IV-oxide (515) was prepared by the reaction of /3-dimethylaminoacrylaldehyde and methyl nitroacetate (74IZV845). 

Attempts to prepare bis-quaternaiy salts from pyridazine and methyl iodide, ethyl bromide, or l,4-dibromobut-2-ene were unsuccessful. ... 

It is likely that initially the open-chain adducts 353 and 354 are formed by the addition of an amino group either to the carbonyl function or to the triple bond, whereupon these intermediates close up to the azepines 355 and their bis-imine tautomers 356. In the H NMR spectra, the methylene protons of 356 are at 2.85-2.97 ppm, whereas the methyl protons are fixed at 2.20-2.27 ppm. The IR spectra show absorption bands corresponding to the aromatic ring (1600 cm ) and to the diazepine cycle C=N double bonds (1580 cm ). However, there are no bands of... 

UV spectra of a variety of 1 -alkyl-1 //-1-benzazepines,20,21 3//-l-benzazepines,20 l-acyl-l//-l-benzazepines,1 3,22,23 3-acyl-3//-3-benzazepines,22-23 3-alkyl-37/-3-benzazepines and their cations in concentrated sulfuric acid,24,25 and 3-mesyl-3//-3-bcnzazepine,2ft have been recorded. A comparison of the UV spectra of 3-alkyl-l, 5-dihydroxy-3//-3-benzazepinc-2,4-dicarboxylates and their bis-O-methyl ethers supports an enol rather than an amide structure for these derivatives.14... 

Condensation of 165 with ethoxymethylenemalononitrile gave 171, and with ethyl ethoxymethylenecyanoacetate or methyl bis(methylmercapto)-methylene cyanoacetate it yielded 172 (80AP108). The reaction of 172 with urea, thiourea, and benzyl nitrile afforded 173 (91PHA98). Treatment of hydrazino derivatives 165 with alkyl, aryl, or aralkyl isothiocyanates yielded (86JHC1731) 3-(/V-substituted-thiocarbamoyl)-hydrazino[l,2,4]triazino[5,6-b]indoles which have been evaluated for in vitro antimicrobial activity (Scheme 36). 

In a related study the adduct of the lithium enolate of methyl bis(trimethylsilyl)acetale and ( —)-(/J)-2-(4-methylphenylsulfinyl)-2-cyclopentanone was transformed to ( — )-methyl jasmonate in > 99% ee. In contrast to the previous study described in this section, addition of the enolate proceeded apparently through a chelated form of the enone15. 

PET is the polyester of terephthalic acid and ethylene glycol. Polyesters are prepared by either direct esterification or transesterification reactions. In the direct esterification process, terephthalic acid is reacted with ethylene glycol to produce PET and water as a by-product. Transesterification involves the reaction of dimethyl terephthalate (DMT) with ethylene glycol in the presence of a catalyst (usually a metal carboxylate) to form bis(hydroxyethyl)terephthalate (BHET) and methyl alcohol as a by-product. In the second step of transesterification, BHET... 

An interesting example for the preparation of functional disiloxanes by use of organometallic techniques is the synthesis of l,3-bis(4-hydroxybutyl)t.etramethyl-disiloxane as shown in React ion Scheme VI. The first, part of the reaction is conducted at the reflux temperature of tetrahydrofuran (THF) and methyl iodide is used as catalyst. The ratio of dichlorodimethylsilane to magnesium and to THF affects the yield of the cyclic product very strongly. The disiloxane is obtained in about 70% yield by aqueous hydrolysis of the purified cyclic intermediate under mild conditions and in the presence of a small amount of hydrochloric acid. 

We extended the kinetic model to other monomer systems such as styrene and methyl methacrylate. With these, we used common initiators such as benzoyl peroxide and azo-bis-isobutyronitrile. The results of these simulations compared closely with some published experiments. 

Methyl 3-chloro-2-quinoxalinecarboxylate (113) gave a separable mixture of A,A -bis(3-methoxycarbonylqumoxalin-2-yl)hydrazine (114) and methyl 3-hydrazino-2-quinoxalinecarboxylate (115) [substrate, H2N1SIH2 H20 ( 1 equiv), EtOH, 20°C 70°C, short time 25% of each product after separation] or 3-hydrazino-2-qumoxalinecarbohydrazide (116) [H2N1SIH2 H20 ( 2.5 equiv), EtOH, 70°C, substrate during 30 min 95%]. °... 

Bis(hydroxymethyl)quinoxaline 1,4-dioxide (dioxidine 173, R = H) and methyl isocyanate gave 2,3-bis(A(-methylcarbamoyloxymethyl)quinoxaline 1,4-dioxide (173, R = CONHMe) (for details, see original). 

The reaction of crotonaldehyde and methyl vinyl ketone with thiophenol in the presence of anhydrous hydrogen chloride effects conjugate addition of thiophenol as well as acetal formation. The resulting j3-phenylthio thioacetals are converted to 1-phenylthio-and 2-phenylthio-1,3-butadiene, respectively, upon reaction with 2 equivalents of copper(I) trifluoromethanesulfonate (Table I). The copper(I)-induced heterolysis of carbon-sulfur bonds has also been used to effect pinacol-type rearrangements of bis(phenyl-thio)methyl carbinols. Thus the addition of bis(phenyl-thio)methyllithium to ketones and aldehydes followed by copper(I)-induced rearrangement results in a one-carbon ring expansion or chain-insertion transformation which gives a-phenylthio ketones. Monothioketals of 1,4-diketones are cyclized to 2,5-disubstituted furans by the action of copper(I) trifluoromethanesulfonate. ... 

Fig. 27.—The rate of copolymerization of styrene and methyl methacrylate at 60°C in the presence of azo-bis-isobutyronitrile (1 g./l.) plotted against the mole fraction of styrene. Broken line has been calculated from Eq. (26) assuming < = 1. Solid line represents calculated curve for 0 = 13. (Walling. q...

Although their source has not been identified, it has been shown that volatile compounds from landfills contain carbonyls of Mo and W in addition to the known hydrides and methylated derivatives of As, Se, Sn, Sb, Te, Hg, Pb, and Bi (Eeldmann and Cullen 1997). 

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