And antipsychotic drugs

The antianxiety dragp are discussed in this chapter. Antidepressant dragp and antipsychotic drugs are discussed in Chapters 31 and 32, respectively. 

Groves. P.M., and Rebec, G.V. Biochemistry and behavior Some central actions of amphetamine and antipsychotic drugs. Ann Rev Psychol 27 91-127, 1976. 

Benzodiazepines and antipsychotic drugs are associated with cognitive impairment and increased risk of falls... 

Other orthopramides have been shown to be resistant to in vivo hydrolysis. Thus, the gastrokinetic drug cisapride (4.80) was not hydrolyzed after oral administration to dogs and humans [51]. Similarly, sulpiride (4.81), an antidepressant and antipsychotic drug, did not undergo hydrolysis in humans and laboratory animals. These compounds are metabolized by other routes, and hydrolysis of the amide bond, when it occurs at all, is only a minor pathway. 

For example, it can be used to understand the SAR overlap " of the 5-HT2a antagonist and antipsychotic drug sertindole at hERG, sodium and calcium channels as shown in Fig. 10. 

Jones, HM, Pilowsky, LS. Dopamine and antipsychotic drug action revisited. Br J Psychiatry 2002 181 271-5. 

Breier A Serotonin, schizophrenia and antipsychotic drug action. Schizophr Res 14 187-202, 1995... 

Costall B, Naylor RJ 5-HT receptors and antipsychotic drugs, in Central Serotonin Receptors and Psychotropic Drugs. Edited by Marsden CA, Heal DJ. London, Blackwell Scientific, 1992b, pp 198-221... 

Analogous to the recent progress in antidepressant and antipsychotic drug therapy development the pharmacotherapy of bipolar disorder is also experiencing major advances. Data on the efficacy of mood stabilizers for bipolar disorder focus on the following ... 

Table 13-2. Weight gain and antipsychotics (drugs listed in order of increasing weight gain likelihood)...

As part of a comprehensive rehabilitation program, prescription medications may help recovering substance abusers with persistent mental health needs. For example, anti-anxiety medications such as diazepam (Valium) and antipsychotic drugs such as haloperidol (Haldol) may address acute needs. 

Kinan, B. J. and Lieberman, J. A. Mechanism of action of atypical and antipsychotic drugs - a critical analysis. Psychopharmacol. 124 (1996) 2-12. 

Serotonin and Dopamine Interactions in Rodents and Primates Implications for Psychosis and Antipsychotic Drug Development... 

Jakab RL, Goldman-Rakic PS. 5-Hydroxytiyptamine(2A) serotonin receptors in the primate cerebral cortex Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites. Proc Natl Acad Sci USA 1998 95 735-740. 

Johnson SA, Luu NT, Herbst TA, Knapp R, Lutz D, et al. 1999. Synergistic interactions between ampakines and antipsychotic drugs. J Pharmacol Exp Ther 289 392-397. 

Dean B, Pavey G, Thomas D, Scarr E. 2006. Cortical serotonin , ID and IF receptors Effects of schazophrenia, suicide and antipsychotic drug treatment. Schizophr Res 88 265-274. 

While the efficacy of lithium alone or in combination continues to be reconfirmed, drawbacks related to adherence to therapy or genetic links to poorer outcomes have also been highlighted. For those reasons, alternatives to lithium, such as anticonvulsants and antipsychotic drugs, have often been discussed (77). However, several studies have reconfirmed the efficacy of lithium in acute mania and its equivalence to some of the newer options. 

Baldwin D, Mayers A. Sexual side-effects of antidepressant and antipsychotic drugs. Adv Psychiatr Treat 2003 9 202-10. 

Viala et al. published a method for GC detection of chloroquine and monodes-methylchloroquine in hair of patients who had been treated with chloroquine for several months. The samples were washed with detergent (DET) and then dissolved in hot potassium hydroxide. After the extraction with ether, a thin-layer procedure was used for cleaning up. The quantitation was made by GC with a NP-FID. Chloroquine and its metabolite were identified by GC/MS. The GC detection of chloroquine and with NP-FID detector was reported by Ochsendorf et al. They quantitated the drug in different hair sections and found a correlation to the pharmacological behavior of the substance. Couper et al. described a GC screening with NP-FID for antidepressants and antipsychotic drugs in hair from post-mortem cases. 

Couper, F. J., McIntyre, I. M., Drummer, O. H., Detection of Antidepressant and Antipsychotic Drugs in Post-Mortem Human Scalp Hair, J. Forensic Sci., 40, 87, 1995. 

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