Analysis animal origin

As a special service, the German authority has published reviews on residue analysis concerning new a.i. contained in plant protection since 1996, including selected physical-chemical data. Recoveries obtained in fortification experiments and LOQs for analytical methods for determination in crops, food of plant and animal origin. 

N. Haagsma and C. van der Water, Immunochemical methods in the analysis of veterinary drug residues, in Analysis of Antibiotic Drug Residues in Food Products of Animal Origin, ed. V. K. Agarwal, Plenum Press, New York, pp. 81-97 (1992). 

Several qualitative and quantitative immunochemical methods for CAP analysis in biological matrices of animal origin have been described [101,102, 104,105] (see Table 3). Van de Water et al. [ 102] described an ELISA that detected CAP in swine muscle tissue with an IC50 value of 3 ng mL1. This immunoassay was improved and subsequently optimized incorporating the streptavidin-biotin amplification system. There are also several commercially available test kits (see Table 4). RIDASCREEN is a competitive enzyme immunoassay for the quantitative analysis of CAP residues in milk, eggs, and meat in a microtiter plate. The measurement is made photometrically, obtaining a LOD of 100 ng L 1 in meat and eggs and 150 ng L 1 in milk. The test has been also applied to the analysis of tetracyclines. 

In contrast to milk, where samples are primarily derived from cows, meat analysis has to be performed in samples of a widely different animal origin including cattle, lamb, swine, poultry, and fish. Muscle is a complex matrix with a pH of 5.7, composed of muscle fibers, various types of connective tissue, adipose tissue, cartilage, and bones. Sarcoplasmic proteins such as myoglobin, and glycolytic enzymes are soluble in water while the myofibrillar proteins such as myosin and actin are soluble in concentrated salt solutions (14). The connective tissue proteins, collagen and elastin, are insoluble in both solvents. 

C. van de Water, in Development of Immunochemical Procedures for the Analysis of Chloramphenicol Residues in Food of Animal Origin, Thesis, University of Utrecht, The Netherlands (1990). 

Samples for analysis can come from products of vegetable or animal origin (milk, meat), water, air (ashes emitted by an incinerator) or soils in which elements are present over a wide range of concentrations (from manure spreading on agricultural land to industrial sludge). This method also has applications in the area of forensic sciences and clinical medicine (tissue analysis or biological fluids). 

E-S Tee, C-L Lim. Re-analysis of vitamin A values of selected Malaysian foods of animal origin by the AOAC and HPLC methods. Food Chem 45 289-296, 1992. 

The EU has adopted several directives setting the MRLs for pesticides, including OCPs and OPPs, in fruit and vegetables (90/642/EEC), cereals (86/362/EEC), and foods of animal origin (86/363/EEC). One of the main concerns in pesticide residue analysis is to reach detection limits as low as 0.1 yug/L, which is the MLR established by the EU for drinking water (80/779/ EEC) (28,29). 

Q5B nology Products derived from Cell Lines of Human or Animal Origin Quality of Biotechnological Products Analysis of the Expression Construct CPMP/ICH/139/95 Step 5... 

RMs for chemical composition (steels, alloys, gases in metals, biological materials of plant and animal origin, geological materials, ores, materials for clinical analysis, glasses, ceramics, etc.)... 

Most measurements for organochlorine compounds have been undertaken on human serum and milk, but analysis of urine and abdominal fat has also been made. Analysis of food has concentrated on high fat-containing foods of animal origin. All analyses have been performed by gas-chromatographic techniques. 

Eugster (2003, 2004) reported applications of the method for the detection of contaminations of animal origin in vegetable samples. The analysis of food control samples of cereal flours, cereal dust, and cereal products resulted in several findings of animal contamination by small rodents and insects. In vegetable feedstuffs with the... 

PSA/C18 combination is more widely used in the analysis of food of animal origin because of the higher lipid content. In more recent research, it was found that the combination of PSA and C18 provided better clean-up than did PSA or Cl8 alone for 38 anthelmintics in liver and milk. " However, PSA/C18 gave a lower recovery for some analytes (due to PSA), compared with Cl8 alone, which gave sufficient clean-up and good recovery for all analytes and was therefore chosen as the preferred sorbent. 

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