Analogous products

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Certain bifunctional nucleophiles allow cyclization after ring opening. The formation of 2-thiazolium salts (71JHC40S) and the analogous production of 2-amino-2-thiazolines (191) from aziridines and thiocyanic acid fall into this category (72JOC4401). 

Analogous products are obtained from thermolyses of chlorodiazirines bearing ethyl, propyl, isopropyl or r-butyl groups. 

The unsaturated tetraoxaquaterene (accompanied by linear condensation products) was first synthesized in 18.5% yield by the acid-catalyzed condensation of furan with acetone in the absence of added lithium salts. Other ketones also condensed with furan to give analogous products in 6-12% yield.A corresponding macrocycle was also prepared in 9% yield from pyrrole and cyclohexanone. The macrocyclic ether products have also been obtained by condensation of short linear condensation products having 2, 3, or 4 furan rings with a carbonyl compound. ... 

Sbisido (1938) bas confirmed tbe identity of tbe syntbetie and natural alkaloids, by showing that the two methyl ethers on degradation by tbe Hofmann process yield 5 6-dimethoxy-2 3-methylenedioxy-8-vinylphenanthrene, m.p. 142-3°, and the two ethyl ethers the analogous product with ethoxy- replacing the methoxyl group at C . 

Sanna reported that l,3-di(3-indolyl)-l,3-dioxo-%-propanc (266) and l,4-di(3-indolyl)-l,4-dioxo-M-butane (267) were formed by the action of malonyl chloride and succinyl chloride, respectively, on the indole Grignard reagent in ether, and analogous products could be obtained from 2-methylindole. 

A crystalline addition product of indole with picryl chloride (i.e. l-chloro-2,4,6-trinitrobenzene), together with an unidentified amorphous substance, were obtained by the action of picryl chloride on indole magnesium iodide, and analogous products were obtained in the reaction between the indole Grignard reagent and 1-chloro-2,4,5-trinitrobenzene. 

A number of pentacyclic quaternary j8-carbolinium derivatives undergo reactions in which the hetero ring is cleaved. Thus semper-virine (286) is converted in poor yield into the indole derivative 287 on catalytic hydrogenolysis with Raney nickel. Alstonine and serpentine yield the analogous product on treatment with selenium. 

Dimethylquinoxaline undergoes reaction with typical dienophiles such as maleic anhydride, p-benzoquinone, and AT-phenylmaleimide. The products were formulated as Diels-Alder adducts primarily since analogous products were not isolated from reactions with other quin-... 

A series of phosphorus- and bromine-containing FRs were synthesized and studied to understand their role, especially their combined effects. Thus, monocar-danyl phosphoric acid, its bromo derivatives and their formaldehyde condensates and crosslinked products [28,188] were prepared and their properties compared with analogous products made from phenol [28,189]. Table 14 gives the LOI values, char yields (Cy at 600°C), and thermal stability at 50% (T6o) decomposition. 

The reduction of carbonyl compounds by reaction with hydride reagents (H -) and the Grignard addition by reaction with organomagnesium halides (R - +MgBr) are examples of nucleophilic carbonyl addition reactions. What analogous product do you think might result from reaction of cyanide ion with a ketone ... 

Substituting benzene-1,2-diamine by diaminomaleonitrile gives an analogous product 13 in this case the cyclobutaquinoxalinc intermediate could not be isolated.35... 

Several of these oxadiazoloquinoxaline 5-oxides have been converted into quinoxaline 1,4-dioxides. For example, 2-oxo-2//-[l,2,4]oxadiazolo[2,3-a]quinoxa-line-4-carbonitrile 5-oxide (572) in refluxing ethanol or 2-propanol for 2 h gave 3-ethoxycarbonylamino- (573, R = Et) or 3-isopropoxycarbonylamino-2-quinoxa-linecarbonitrile 1,4-dioxide (573, R = Pr ) in 61% or 74% yield, respectively 10 other analogous products with 6- and/or 7-substituents were made unambiguously in a similar way. ... 

The same substrate (25) aud ethyl 2-chloroacetoacetate gave an analogous product, ethyl 3-hydroxy-3-methyl-3,4-dihydro-2//-1,4-thiazino[2,3-h]qui-noxahne-2-carboxylate (27) (KOH, EtOH, 20°C, 3 h 58%), which underwent dehydration to ethyl 3-methyl-2H-1,4-thiazino[2,3-h]quinoxaline-2-carboxy-late (28) (HCl gas, EtOH, 20°C, 15 h 60% analogs likewise). ... 

EtOH, reflux, 2 h 27% many analogous products likewise). 

The oxidations of 2-chloro- and 2-hydroxycyclohexanone by IrClg " show the same general kinetic behaviour, indicating prior enolisation, and analogous products, i.e. dichlorocyclohexanone and IrClsOH " from chlorocyclohexanone (ref. ). 

Combined treatment of atrazine with ozone and H2O2 resulted in retention of the triazine ring, and oxidative dealkylation with or without replacement of the 2-chloro group by hydroxyl (Nelieu et al. 2000). Reaction with ozone and hydroxyl radicals formed the analogous products with the additional formation of the acetamido group from one of the N-alkylated groups (Acero et al. 2000). 

Methyl-2( 1 //)-quinoxalinone gave 3-(o-chlorophenylhydrazono)methyl-2( 1H)-quinoxalinone [i.e., 3-oxo-3,4-dihydro-2-quinoxalinecarbaldehyde o-chloro-phenylhydrazone (170)] [0-CIC6H4N2CI (made in situ), HCI-ACOH-H2O, 5°C, 30 min then 95°C, 1 h 98% 20l,210,cf 220 likewise the m- and p-isomers201,210 and analogous products.476,479,485... 

Analogous products are obtained if 2-fury lmethylamine, di-n-propylamine, or -(1,5-dimethyl)hexylamine are used instead of NH3, with yields of 67, 88 and 84%, respectively. 

In an effort to further support the proposed mechanisms for the Y+propene reaction, we have examined the reactions of Y with four isomeric butenes, which are essentially propene molecules with one additional methyl group (Fig. 31). Based on estimated potential energy barrier heights22 and thermodynamics (Fig. 32))22-31-34,i56,i57 q js eXpected that analogous product channels to those observed for propene should be seen for the butenes. Therefore, a comparison of reactions of butene isomers to reactions with propene should allow us to further test the validity of the proposed mechanisms. Here we briefly summarize our most notable conclusions from this work. 

In a similar manner, aminotriazole 260 has been condensed with 1 -mcthyM-m ethyl sulfanyl-2,5-dioxo-2,5-dihydro-17/-pyrrole-3-carbonitrile 262 to give rise to analogous product 263 (Equation 72) <1996H(43)1597>. 

The oxidative addition of hexafluoroacetone to 221 gives 222 (X = CH) in which chloromethane has been eliminated in a ring-closing step to give a product with a bridgehead phosphorus center (Scheme 28). Analogous products 223 were obtained by treatment of 221 (X = N) with hexafluoroacetone (Scheme 29) <2000ZFA412>. The oxidative addition was found to be reversible. 

Analogous products have been obtained when salicylic aldehyde was replaced by o-hydroxynaphthaldehyde. 

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