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Analgesics dental

Flupirtine (23) administered as the maleate, is a centrally active, nonaddicting analgesic shghtly more potent than aspirin and is especially useful m the management of postoperative and dental pain [20]... [Pg.1122]

There have been numerous clinical studies examining the analgesic effects of TCAs in chronic pain, and the review of these is beyond the scope of this chapter. There are a number of reviews covering these studies (e.g. Onghena and van Houdenhove, 1992 McQuay et al., 1996 Feuerstein, 1997). In contrast, the effects of TCAs in acute pain have not received much attention in clinical research. There are only a few controlled studies with mixed results, reporting no effect of desipramine or amitryptiline on postoperative dental pain when given alone but enhanced... [Pg.269]

Oral ibuprofen is often prescribed in lower doses (< 2400 mg/d), at which it has analgesic but not anti-inflammatory efficacy. It is available over the counter in low-dose forms under several trade names. A topical cream preparation appears to be absorbed into fascia and muscle an (S)( ) formulation has been tested. Ibuprofen cream was more effective than placebo cream for the treatment of primary knee osteoarthritis. A liquid gel preparation of ibuprofen 400 mg provided faster relief and superior overall efficacy in postsurgical dental pain. In comparison with indomethacin, ibuprofen decreases urine output less and also causes less fluid retention than indomethacin. Ibuprofen has been shown to be effective in closing patent ductus arteriosus in preterm infants, with much the same efficacy and safety as indomethacin. Oral ibuprofen is as effective as intravenous administration in this condition. [Pg.820]

Aluminum compounds are also used extensively in the manufacture of cosmetics (e.g., aluminum hexahydrate in deodorants) and in medical treatments (e.g., aluminum hydroxide in antacids to control gastric hyperacidity or aluminum oxide in dental ceramic implants) (Brusewitz 1984 NRC 1982). In addition, antacids and buffered aspirin contain 4-562 mg/kg (ppm) of aluminum (Schenck et al. 1989 Shore and Wyatt 1983). Lione (1985a) reported aluminum content/dose (single tablet or 5 mL liquid) for antacids, internal analgesics (buffered aspirins), antidiarrheals, and anti-ulcerative drugs (Table 5-7). [Pg.233]

Eugenol has been used since the nineteenth century as a flavoring agent in a variety of foods and pharmaceutical products. It has found use as a mild rubefacient in dentifrices, and as an obtundent for hypersensitive dentine, caries, or exposed pulp. Additional uses are in dental cement preparations, analgesics and anesthetics, and temporary dental filling when mixed with zinc oxide. The substance is also used in the perfumery or flavor industries, and also as insect attractant [1, 3, 4]. [Pg.153]

Darvon is a stronger analgesic than aspirin but has no antipyretic effects. It is sometimes taken in combination with aspirin and acetaminophen. It has widespread use for dental pain since aspirin is relatively ineffective, but it is not useful for deep pain. [Pg.188]

Rofecoxib is approved for the treatment of acute pain and dysmenorrhea at a dose of 50 mg for up to 5 days. The clinical studies indicate that rofecoxib shows efficacy similar to that produced by the maximum analgesic doses of naproxen and ibuprofen (Ehrich et al., 1999). The pain settings in which rofecoxib has been tested include acute postoperative dental pain, the pain of dysmenorrhea for up to 3 days, and postoperative pain for 5 days following surgical replacement of the knee or hip. In contrast, celecoxib is not approved in the United States for the treatment of acute pain, and it appears to be less effective when given acutely than rofecoxib, ibuprofen, or naproxen. The explanation for the differences between rofecoxib and celecoxib in acute pain is not known. [Pg.129]

A review of drug interactions with analgesics in the dental literature concluded that NSAIDs should be used briefly, if at all, in patients taking lithium, especially in the... [Pg.162]

Haas DA. Adverse drug interactions in dental practice interactions associated with analgesics. Part III in a series. J Am Dent Assoc 1999 130(3) 397-407. [Pg.182]

Dionne RA, Wirdezk PR, Butler DP, Fox PC. Comparison of conorphone, a mixed agonist-antagonist analgesic, to codeine for postoperative dental pain. Anesth Prog 1984 31(2) 77-81. [Pg.900]

Morrison BW, Christensen S, Yuan W, Brovm J, Amlani S, Seidenberg B. Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in post-dental surgery pain a randomized, controlled trial. Chn Ther 1999 21(6) 943-53. [Pg.1012]

Desjardins PJ, Cooper SA, Gallegos TL, Allwein JB, Reynolds DC, Kruger GO, Beaver WT. The relative analgesic efficacy of propiram fumarate, codeine, aspirin, and placebo in post-impaction dental pain. J CUn Pharmacol 1984 24(1) 35 2. [Pg.2945]

Therefore, it would not be uncommon for a dentist to prescribe analgesic medication on a non-NHS (private) prescription form for a patient under his care, even if that item was not in the Dental Practitioners Formulary (see Section 3.2.2). However, it would be unusual for them to prescribe, for example, medication for the treatment of schizophrenia. If a pharmacist received a non-NHS (private) prescription form from a dentist for medication to treat schizophrenia, the pharmacist should query the supply with the prescribing dentist to confirm that the dentist is prescribing within their area of competence. [Pg.124]


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