3-aminopropyltriethoxysilane APTES

CNTs offer an exciting possibility for developing ultrasensitive electrochemical biosensors because of their unique electrical properties and biocompatible nanostructures. Luong et al. have fabricated a glucose biosensor based on the immobilization of GOx on CNTs solubilized in 3-aminopropyltriethoxysilane (APTES). The as-prepared CNT-based biosensor using a carbon fiber has achieved a picoamperometric response current with the response time of less than 5 s and a detection limit of 5-10 pM [109], When Nation is used to solubilize CNTs and combine with platinum nanoparticles, it displays strong interactions with Pt nanoparticles to form a network that connects Pt nanoparticles to the electrode surface. The Pt-CNT nanohybrid-based glucose biosensor... 

Anodic EOF for CEC has also been obtained on a silica hybrid synthesized with the two coprecursors TEOS and 3-aminopropyltriethoxysilane (APTES) [97]. Here, no catalyst was added to accelerate the hydrolysis and condensation reactions ... 

Fig. 6 Common silanizing trialkoxysilanes that promote covalent DNA immobilization a 3-aminopropyltriethoxysilane (APTES) b 3-aminopropyltrimethoxysilane (APTMS) c 3-glycidoxypropyltrimethoxysUane (GOPS) d 3-mercaptopropyltrimethoxysilane (MPTS)...

Huq and Mercier191 synthesized cyclodextrin modified silicas by first coupling the cyclodextrin units to 3-aminopropyltriethoxysilane (APTES) and then subjecting it to a co-condensation reaction with TEOS (Fig. 3.15c). Interestingly, all attempts to anchor cyclodextrins by grafting onto previously thiol-functionalized silicas have been unsuccessful. It has also been demonstrated that the cyclodextrin units on the... 

In many cases, silicon organic compounds are used as connecting links between a silica surface and a biomolecule. The most popular technique utilizes the modification of a hydroxy-functionalized surface with 3-aminopropyltriethoxysilane (APTES) [2] followed by crosslinking with glutaraldehyde (GA) (Fig. 1 A). 

A Immobilization with 3-aminopropyltriethoxysilane (APTES) and glutaraldehyd (GA) B Immobilization using aldehyd-fimctionalized ethoxysilanes... 

The prominent goal of these studies was the detection of interactions between substrate and silyl esters with different organic groups R. The model substrates used include various kinds of silica, alumina, titania in addition to typical sandstones and silicon wafers. With respect to a contribution in the first conference report [3] one example may suffice here to demonstrate the procedure and the importance of the result obtained. The example concerns the treatment of a silicon wafer surface with 3-aminopropyltriethoxysilane (APTES) aimed at the detection of covalent bonding and possible interaction of the functional aminopropyl group with reactive surface centers. The method of choice is a... 

Organic ligands added to sol solutions can be used to control NC growth and size dispersities. " This approach, analogous to the method described for metal NCs in Section 2.1, employs bifunctional linkers to tether metal salts to the sol-gel network to improve the homogeneity of the sample. Silica precursors mixed with 3-aminopropyltriethoxysilane (APTES) and cadmium nitrate were allowed to gel. Following oxidative treatments, the resulting CdO particles were converted to CdS upon exposure to H2S, as shown in equation (4). The size distribution of particles was much narrower under these conditions than when APTES was omitted from the reaction. 

Fig. 7.4. Functionalization of Pt/Au surface via 3-aminopropyltriethoxysilane (APTS) for the development of an immunosensor for the detection of anti-cyanazine.

They were treated with 2% 3-aminopropyltriethoxysilane (APTES) in dry toluene for 2 h. 

As it was mentioned above, as far back as 1966 a method was advanced for producing aminoorganosUica gel by hydrolysis of 3-aminopropyltriethoxysilane (APTES) [or of its mixrnres with tetraethoxysilane (TEOS)] in an alkali medium [11]. The procedure for producing poly (3-aminopropyl)siloxane (PAPS) xerogel involved interaction of a mixrnre TEOS/APTES (42 15 cm ) in 50 cm of methanol in the presence of 10 cm of a 0.5 M solution of NaOH. The obtained gel was washed for 7 days up to the neutral reaction of washing waters and dried at 120°C up to constant sample weight. The adsorptive capacity of the sorbent with respect to methacrylic acid was equal to 1.6 cm /g. 

In related research gadolinium oxide nanoparticles with the composition Gd20 (003)2 H2O were studied by Hu et al. (Figure 7.7). The gadolinium oxide particles were synthesized by the hydrolysis of gadolinium chloride in the presence of urea to form white spheres of 441 nm. A silica shell was then deposited on the particle surface by the hydrolysis of TFOS. Amination of the silica was carried out by reaction with 3-aminopropyltriethoxysilane (APTES) and was followed by the... 

Finally, we reported last year an easy preparation of a bis-zwitterionie lamellar material containing ammonium carboxylate groups by a sol-gel process using ethylenediamine as bridging groups.This material was prepared in one step by a sol-gel process from only 3-aminopropyltriethoxysilane (APTES), succinic anhydride, and ethylene diamine (Scheme 12.18). 

UV irradiation of H-terminated diamond covered with liquid films of an appropriate alkene [177] is also viable. The addition of aminosilane groups to the diamond surface is possible by reacting O-terminated diamond with 3-aminopropyltriethoxysilane (APTES). Carboxylation of the surface involves reacting an aminated surface with succinyl chloride and triethyl amine [178]. 

The complexes of Co(II) with salen and salophen were prepared according to [9,10]. The poly(3-aminopropyl) siloxane matrix (SAP) was obtained by the procedure [11] with some small modifications of this method [12]. Tetraethoxysilane (TEOS) and 3-aminopropyltriethoxysilane (APTES) (Aldrich) were used without previous pimfication. 

Due to its similar chemical nature, oxidized porous Si (porous Si02) can be modified using many of the same chemistries used to modify silica or glass surfaces. This includes a wide range of conventional silanol-based chemistries (Janshoff et al. 1998 Tinsley-Bown et al. 2000 Schwartz et al. 2005). One of the most popular coupling reactions is the reagent 3-aminopropyltriethoxysilane (APTES), Eq. 17. Because it places a reactive —NH2 group on the surface, APTES is very commonly used to link molecules such as proteins and DNA to silica (Anderson et al. 2008), oxidized silicon (Nijdam et al. 2007), and oxidized porous Si (Tinsley-Bown et al. 2000) surfaces. 

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