Aminocarb

IUPAC name 4-dimethyamino-m-tolyl methylcarbamate Molecular formula CiiH16N202 Toxicity class USEPA II WHO II 

Aminocarb is a nonsystemic insecticide. It controls lepidopterous insects, aphids, and soil mollusks. The acute oral LD50 for rats is 50 mg/kg, and the acute dermal LD50 for rats is 275 mg/kg, suggesting that toxicity to skin is appreciably severe compared with carbamate pesticides.2 

Uses Isoprocarb is a colorless crystal. It is used as an insecticide for aphids, bugs, and leafhoppers that attack and infect crops such as rice, sugarcane, and cocoa. Formulations of isoprocarb include wettable powder, emulsion concentrate, and granules.1,2 

Toxicity The acute oral LD50 of isoprocarb for rats is 450 mg/kg, and acute dermal LD50 for rats is more than 500 mg/kg. The acute LC50 (4 hours) for rats is 0.5 mg/L. It is slightly irritating to the skin of rabbits. 

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High performance Hquid chromatography with electrochemical detection has been used to determine 2—7 ppb of carbamate pesticides in water (40). The investigated pesticides were aminocarb, asulam, j -butylphenyknethylcarbamate (BPMC), carbaryl, carbenda2im, chlorpropham, desmedipham, and phenmedipham. 

Pesticides, e.g. aminocarb, captan, difolatan, landrin, rotenone... 

Pesticides, e.g. aminocarb, captan, difolatan, landrin, rotenone 200 °C, 45 min Induction of fluorescence in weakly [ fluorescent or nonfluorescent pesticides and amplification of natural fluoies-cence. There are some differences between basic and acidic aluminium oxide layers. 

Chemicals. Insecticides, at least 95% pure, were prepared as acetone solutions p-p DDT, lindane, parathion, paraoxon, malathion, malaoxon, propoxur, carbaryl, LandrinR, aminocarb, mexacarbate, allethrin (90%), piperonyl butoxide (PBO) and sesamex. Aldrin was 98.5% and dieldrin was 99+% pure. 

Low synergistic ratios indicating antagonism by PBO (ratios from 0.15 to 0.33) were obtained with aldrin, parathion, malathion, aminocarb, and mexacarbate. PBO strongly synergized allethrin (SR 102). Assays where synergism was weak or absent... 

Aminocarb [2032-59-9] Gammarus pseudolimnaeus EC50 (24-h) 0.55 Mayer and Ellersieck, 1986... 

Amino-4-hydroxymethyl benzoate, see Phenmedipham 2-Amino-6-hydroxymethyl benzoate, see Phenmedipham 2 -Amino-2-hydroxypropiophenone, see Nanronamide 4-Amino-6-(isopropylamino)-s-triazine, see Prometrvn 2-AminoAV-isopropylbenzamide, see Bentazone 4-Amino-3-methylphenol, see Aminocarb... 

Formamide, see Pyridine 4-Formamido-m-tolyl-lV-methylcarbamate, see Aminocarb... 

Methylbenzimidazole, see 2-Nitroaniline Methyl 2-benzimidazole carbamate, see Benomvl Methyl benzoate, see Sulfometuron-methvl 4-Methyl-2//-l-benzopyran-2-one, see Naphthalene o-Methylbenzoquinone, see Aminocarb p-Methylbenzoquinone, see Toluene... 

Phenol, see Aminocarb. Benzene, Bromobenzene, Carbaryl, Chlorobenzene, 2-Chlorobiphenvl. 4 Chlorobiphenvl. 1,4-Dichlorobenzene, Hexachlorobenzene, Hydroquinone, 4-Methylphenol, Naphthalene, Pentachlorobenzene, Toluene, 1,2,3-Trichlorobenzene Phenoxazinone, see Phosalone Phenoxyacetic acid, see 2,4-D... 

CASRN 2032-59-9 molecular formula C11H16N2O2 FW 208.26 Plant/Surface Water. Several transformation products reported by Day (1991) include 4-amino-/n-tolyl-7V-methylcarbamate (AA), 4-amino-3-methylphenol (AC), 4-formamido-/n-tolyl-TV-methylcarbamate (FA), 7V-(4-hydroxy-2-methylphenyl)-yV-methylformamide (FC), 4-methyl-formamido-/n-tolyl-7V-methylcarbamate (MFA), 4-methylamino-/n-tolyl-Wmethylcarbamate (MAA), 3-methyl-4-(methylamino)phenyl-Wmethylcarbamate (MAC), phenol, methylamine, and carbon dioxide. MAA was not detected in natural water but was detected in fish tissues following exposure to aminocarb-treated water in the laboratory. The metabolites FA, AC, and MAC were detected in Canadian forests treated with aminocarb but the metabolites AA, MAA, and FC were not detected (Day, 1991). 

On and/or in bean plants, aminocarb degrades with the carbamate moiety remaining intact. Methylcarbamate derivatives identified include the 4-methylamino, 4-amino, 4-methylformamido, and 4-formamido analogs (Abdel-Wahab et al., 1966). 

Photolytic. When aminocarb in ethanol was irradiated by UV light, extensive degradation was observed. No degradation products were identified however, two unidentified cholinesterase inhibitors were reported (Crosby et al., 1965). 

Chemical/Physical. Aminocarb was hydrolyzed in purified water to 4-(dimethylamin-o)-3-methylphenol before yielding o-methylbenzoquinone. This compound then oxidized to 6-(di-methylamino)-2-methyl-1,4-benzoquinone, 6-(methylamino)-2-methyl-l,4-benzoquinone, 5-(di-methylamino)-2-methyl-1,4-benzoquinone, and 5-(methylamino)-2-methyl-l,4-benzoquinone... 

Leger and Mallet, 1988). When aminocarb was irradiated by a high pressure xenon-mercury lamp (). = 253.7 nm) in aerated and degassed ethanol and cyclohexene solutions, 4-(dimethylamino)-... 

Leger, D.A. and Mallet, V.N. New degradation products and a pathway for the degradation of aminocarb [4-(dimethylamino)-3-methylphenyl IV-methylcarbamate] in purified water, J. Agric. Food Chem., 36(1) 185-189, 1988. 

Richardson. G.M., Qadri, S.U., and Jessiman, B. Acute toxicity, uptake, and clearance of aminocarb by the aquatic isopod, Caecidolea racovitzairacovitzai, Ecotoxicol. Environ. Saf, 7(6) 552-557, 1983. 

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