Amines => azides

Several studies have demonstrated the successful incoriDoration of [60]fullerene into polymeric stmctures by following two general concepts (i) in-chain addition, so called pearl necklace type polymers or (ii) on-chain addition pendant polymers. Pendant copolymers emerge predominantly from the controlled mono- and multiple functionalization of the fullerene core with different amine-, azide-, ethylene propylene terjDolymer, polystyrene, poly(oxyethylene) and poly(oxypropylene) precursors [63,64,65,66,62 and 66]. On the other hand, (-CggPd-) polymers of the pearl necklace type were fonned via the periodic linkage of [60]fullerene and Pd monomer units after their initial reaction with thep-xy y ene diradical [69,70 and 71]. 

Copper amine azide Copper tetramine nitrate Crotonaldehyde, stabilized Cyanogen bromide Cyanuric triazide... 

Te catalyst) reduces tertiary amine iV-oxides to the corresponding amines.Azides are reduced to primary amines by sodium hydrogen telluride. ... 

Thompson, D.M. (2000) Tertiary amine azides in hypergolic liquid or gel fuels propellant systems. US Patent 6,013,143. 

The hydroxyl groups on glycols undergo the usual alcohol chemistry giving a wide variety of possible derivatives. Hydroxyls can be converted to aldehydes, alkyl halides, amides, amines, azides, carboxylic acids, ethers, mercaptans, nitrate esters, nitriles, nitrite esters, organic esters, peroxides, phosphate esters, and sulfate esters (6,7). 

The multicomponent Ugi-type condensation of aldehydes, secondary amines, azide, and polystyrene-bound isonitriles has been reported to yield tetrazoles in acceptable yields (Entry 9, Table 15.20). Tetrazoles have also been prepared from... 

Nucleophilic attack on ( -alkene)Fp+ cations may be effected by heteroatom nucleophiles including amines, azide ion, cyanate ion (through N), alcohols, and thiols (Scheme 39). Carbon-based nucleophiles, such as the anions of active methylene compounds (malonic esters, /3-keto esters, cyanoac-etate), enamines, cyanide, cuprates, Grignard reagents, and ( l -allyl)Fe(Cp)(CO)2 complexes react similarly. In addition, several hydride sources, most notably NaBHsCN, deliver hydride ion to Fp(jj -alkene)+ complexes. Subjecting complexes of type (79) to Nal or NaBr in acetone, however, does not give nncleophilic attack, but instead results rehably in the displacement of the alkene from the iron residue. Cyclohexanone enolates or silyl enol ethers also may be added, and the iron alkyl complexes thus produced can give Robinson annulation-type products (Scheme 40). Vinyl ether-cationic Fp complexes as the electrophiles are nseful as vinyl cation equivalents. ... 

Among the nucleophiles that add exo to coordinated dienes are aUcoxides, amines, azide, acetates, halides, and stabilized carbon enolates, such as malonates and /3-diketones. The alkoxide addition is reversible if the product is treated with HCl. With a few nucleophiles, double addition reactions are observed. Acetate will react with 1,5-cod in the presence of Pb(OAc)4 and palladium salts to give a bicyclic product from addition of two acetate groups, both exo (equation 43). 

Alkali and alkaline-earth metals Alkali-metal alkoxides Antineoplastic alkylating agents Aromatic amines Azides... 

Amin + NOC1), 976/978 (aus A-NO-amin), 999 (aus A-NO-sulfonyl-amid) 1047 (En-Amin + Azid)... 

By suitable choices of substrate such reactions have been used to introduce substituents into the C(i8) and C(i9) methyl groups, and also at various skeletal positions. The necessary free radicals have been generated by fragmentation of iV-halo-amines, azides, nitrites, hypohalites, and also of alcohols, by the action of lead tetraacetate. 

Amine Azide (7o yield) Recovered T0SN3 (%) TosNH- (%)... 

In sulfinyl chlorides (13), the chlorine atom can be easily replaced by various nucleophiles (Scheme 11). This substitution reaction can be used to obtain a range of sulfinyl derivatives. Condensation of the sulfinyl chloride (13) with amines, azide ion, hydrazine, alcohols (or phenols) and thiols thus affords the corresponding sulfinamides (15), azides (16), hydrazides (17), sulfinate esters (18) and thiolsulfinates (19) (Scheme 12).la 2... 

Reactions of epoxides with amines, azides, hydrazines, etc., formation of N-heterocycles by epoxide ring opening 04ZOR11. 

The most common reduction performed on the solid phase is the reductive amination. The reaction has been performed with either resin-bound amine or aldehyde. Reduction of a number of other functional groups has also been applied to the solid phase, usually to generate handles for further diversification, e.g. nitro to amine, azide to amine. 

Relatively easy nucleophilic displacement, via the usual addition/elimination sequence, takes place at all three positions with a wide range of nucleophiles, such as alkoxides, sulfides, amines, azide, cyanide and malonate and related carbanions. ... 

Copper amine azide Cu(NH3)2(N3)2 Dark green crystals explodes when heated to 105°C... 

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