Alkylphenyl derivatives

In this context, it is interesting that the first examples of mesomorphic CT complexes of discoid or sheet-like donor compounds and a strong electron acceptor [7,7,8,8-tetracyano-1,4-quinodimethane (TCNQ)] constitute an exception from the usually observed behavior. These complexes of bi-4-H pyran or bi-4-H thiopyran derivatives carrying four alkyl- or alkyloxy-phenyl substituents with TCNQ (see Fig. 2), have been prepared as organic conductors [40]. The neat alkylphenyl derivatives in the bi-4-H pyran series and alkyl- or alkyloxy-phenyl-substituted bi-4-H thiopyran donors are mesomorphic [40], but the structures of their mesophases are still not clear. 

Derivatives of N-(2,3-dihydrobenzofuran-6-yl)aminomethylene-malonate (806) can be regarded as /V-(3-alkoxyphenyl)aminomethy-lenemalonate derivatives, and those of JV-(2,3-dihydrobenzofuran-5-yl)aminomethylenemalonate (807, R = H) can be regarded as N-(3-alkylphenyl)aminomethylenemalonates. Since the ratio of angular (5-substituted) and linear (7-substituted) products is more sensitive to the circumstances of cyclization in the case of )V-(3-alkylphenyl)aminomethy-lenemalonate (i.e., 807, R = H) than for N-(3-alkoxyphenyl)aminomethy-... 

Two naturally occurring 1,3-oxazine derivatives with a unique, 2-chlorinated tetrahydro-l,3-oxazine structure were reported as metabolites isolated from extracts of the endophytic fungus Geotrichum sp. AL4 <2007MI1520>. Halogenated 3-(4-alkylphenyl)-l,3-benzoxazine-2,4(3//)-diones were found to exhibit antimycobacterial activity <2007AP264>. 

Electrochemically generated cation radical 252 derived from the cyclic alkylphenyl selenide 251 can react via two parallel paths deprotonization with the formation of compounds containing double bonds in the selenium-bearing rings and homolytic cleavage of the C(sp3)-selenium bond, followed by dimerization and formation of a diselenide 253 with an extended ring (Scheme 38) <1987ZOB609>. 

Madelung synthesis. Formation of indole derivatives by intramolecular cyclization of an N-(2-alkylphenyl)alkanamide by a strong base at high temperature. 

Novel alkyldiarylsulfonium salts derived from 9,10-dithiophenoxyanthracene (DTPA) were described by Hacker and Larson [42] in 1988. Alkylation of one sulfur gave the alkylphenyl-(9-thiophenoxyanthracenyl-10)-sulfonium salt (APTAS X). 

In agreement with the finding that within a series of terpenoid / -alkylphenyl ethers the p-ethylphenyl derivatives are the most effective, Solli et al. (1976) prepared a great number of pyridyl terpenoid ethers and found that optimal activity is obtained when the ether bond is in position 3, the alkyl group in position 6 of the heterocyclic nucleus and the substituent is ethyl. Accordingly, the most active representatives of this class are compounds 46 and 47. 

There are general reviews on heterocyclic syntheses by cycloaddition reactions of isocyanates and on the use of heterocyclic cations in preparative organic chemistry. More specific topics are 5-hydroxymethylfuran-2-carb-aldehyde, isobenzofurans and related ort/io-quinonoid systems, the conversion of 2//-cyclohepta[Zj] furan-2-one (1) into derivatives of azulene, the synthesis of indoles from o-alkylphenyl isocyanides, and abnormal Fischer indolization reactions of o-methoxyphenylhydrazones. Two reviews on isoindoles have appeared and a lecture on highly conducting charge-transfer complexes that are based on heterocyclic selenium and tellurium donors has been reprinted.Recent advances in the chemistry of imidazole and in the use of nitro-imidazoles as radiosensitizers have been summarized. There have been reviews on benzimidazole A -oxides and on dihydrobenzimidazoles, benzimidazolones, benzimidazolethiones, and related compounds. Other topics are synthetic applications of 1,3-dithiolium and 1,3-oxathiolium salts and of isoxazoles, the chemistry of benzisoxazoles, 2-amino-oxazoles, 5-oxazolones (2), furoxans, benzofuroxans, and related systems, the synthesis of five-membered meso-ionic compounds, and tetrazoles. ... 

Reactions between diethyl hydrogenphosphonate and ArX (X = I or Br) to give diethyl arylphosphonates have been carried out in the presence of a phase transfer catalyst. Bis(trimethylsilyl) phenylphosphonite reacts with alkyl halides to give [(ar)alkylphenyl]phosphinic derivatives, and it also adds to a,P-unsaturated carboxylic esters (as well as to nitriles and amides) to give (2-functionalized-l-alkyl)phosphinic derivatives. ... 

A great improvement in mesomorphic properties was achieved with the related bis[cj5-2-(4 -alkylphenyl)-3-mercaptopropenato]nickel(II) complexes ((201) R = C H2 +i, >2), and related alkoxy derivatives ((201) R = OC H2 +i, n> 3). Both the alkyl and alkoxy complexes displayed wide nematic temperature ranges typically between about 100 °C and 200 °C the alkyl derivatives possessing lower transition temperatures. 

Wada, Y. Imamoto, T. Tsuruta, H. Yamaguchi, K. Gridnev, I. D. Optically pure l,2-bis[(o-alkylphenyl)phenylphosphino]ethanes and their use in rhodium-catalyzed asymmetric hydrogenations of alpha-(acylamino)acrylic derivatives. Adv. Synth. Catal. 2004,346,777-788. 

Isotherms for the interfacial tension at an aqueous/organic interface show that the new di-(p-alkylphenyl)phosphoric acids 3-6 adsorb at the interface stronger than do commercially available DEHPA (1) or Cyanex 272(2). From the interfacial fluxes for single transition metal cation species transport across a bulk kerosene membrane, the following selectivity orders were derived Zn(II) > Cu(II) > Co(II) > Ni(II) for 1, 5, and 6 Cu(II) > Zn(II) > CoJI) > Ni(II) for 2 and 3 and Cu(II), Zn(II) > CoJI) > Ni(II) for 4. Similar selectivity orders were observed in competitive transport of these transition metal cations across emulsion liquid membranes in which a high utilization degree of the carrier was demonstrated. The di-(p-alkylphenyl)phosphoric acids 3-6 are found to be efficient carriers for proton-coupled transport of transition metal cations from a weakly acidic aqueous source phase across an emulsion liquid... 

In the last decades, an efficient strategy to prepare versatile HBC derivates has been developed.Typically, nanographene molecules can be obtained from the SchoII-type intramolecular oxidative cyclodehydrogenation of polyphenylene precursors with Lewis acid and oxidant (Figure 17). The use of the weaker Lewis acid FeCIs renders the addition of an oxidant unnecessary since FeCIs possesses an oxidation potential sufficient for C-C bond formation. With this protocol, unsubstituted HBC as well as different symmetric alkyl-, alkylphenyl-, and alkylester-substituted HBCs have been prepared in a gram scale with a high yield. 

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