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Alkaloids in biology

For many years, the nature of alkaloids in biology was a mystery. It has been difficult to understand the function of these compounds in plant metabolism. There are many explanations for why plants, animals and micro-organisms produce alkaloids. [Pg.141]

Alkaloids are non-toxic in vacuoles where they are stored but toxic when they escape from the vacuoles. They have to change their chemical configurations and biological activity in different cells and tissues according to pH changes. This means that some alkaloids can have different biological activity in different cell [Pg.142]

Analysis of tropane alkaloids in biological fluids has been developed mostly for cocaine and metabolites. Indeed, it is well recognized that cocaine remains one of the most widely consumed drugs of abuse worldwide. Generally, reversed phase liquid chromatography coupled with UV-VIS detection is employed for these analyses. [Pg.356]

Fu, Q. He, L. Miao, Z. Analysis of strychnine alkaloids in biological samples by thin layer chromatographic densitometry and distribution study of strychnine in intoxicated rats. J. Xi an Med. 1998, 10, 146-149. [Pg.549]

A combination of gas chromatography with other analytical techniques has often been used to ascertain the presence of opium alkaloids in biological fluids. Jain et al. detected... [Pg.116]

An advantage of reversed-phase chromatography in the analysis of alkaloids in biological fluids is that an analysis can be carried out directly without any laborious sample clean-up procedure. However, the use of a precolumn to avoid a too rapid deterioration of the HPLC column is advisable (see Chapter 11). When using aqueous salt solutions in reversed-phase chromatography, one has to be aware of the risk of corrosion of stainless steel columns (see Table 1.3)38. [Pg.226]

HPLC ANALYSIS OF COCAINE AND RELATED ALKALOIDS IN BIOLOGICAL MATERIAL... [Pg.265]

HPLC ANALYSIS ISOQUINOLINE ALKALOIDS IN BIOLOGICAL MATERIALS ... [Pg.296]

TABLE 8.20 HPLC ANALYSIS INDOLE ALKALOIDS IN BIOLOGICAL MATERIAL AND IN TOXICOLOGICAL ANALYSIS ... [Pg.351]

The exact route by which the pyrrole metabolites are formed remains to be established. Although N-oxides are also formed from the alkaloids in biological... [Pg.65]

Quality Parameters for Determining Procyanidins and Alkaloids in Biological Samples by UHPLC-MS/MS... [Pg.367]

Application of UHPLC-MS/MS for Determining Alkaloids in Biological Samples Obtained at Different Times after the Consumption of Cocoa and Chocolate... [Pg.376]

Gas-Liquid Chromatography of Submicrogram Amounts of Drugs. III. Analysis of Alkaloids in Biological Media... [Pg.242]

Namera A, Yashdd M, Hirose Y, Yamaji S, Tani T, Kojima T (2002) Quantitative analysis of tropane alkaloids in biological materials by gas chromatography-mass spectrometry. Forensic Sci Int 130(l) 34- 3. doi 10.1016/s0379-0738(02)00302-x... [Pg.205]

Ciisten P, Bieri S, Venthey J (2008) Analysis of tropane alkaloids in biological matrices. In Fattorusso E, Tagliatela-Scafati O (eds) Modem alkaloids stmcture, isolation, synthesis and biology. Wiley, Weinhein, p 341... [Pg.357]

See other pages where Alkaloids in biology is mentioned: [Pg.141]    [Pg.672]    [Pg.622]    [Pg.341]    [Pg.342]    [Pg.344]    [Pg.346]    [Pg.348]    [Pg.350]    [Pg.352]    [Pg.354]    [Pg.356]    [Pg.358]    [Pg.358]    [Pg.360]    [Pg.360]    [Pg.362]    [Pg.364]    [Pg.366]    [Pg.130]    [Pg.278]    [Pg.306]    [Pg.278]    [Pg.195]    [Pg.196]    [Pg.197]    [Pg.199]    [Pg.201]    [Pg.203]   


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Analysis of Tropane Alkaloids in Biological Matrices

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