Agent Tests

Screen outcome Actual activity of agent tested... 

As mentioned, some 7,000 enlisted men participated in the Edgewood Arsenal chemical agent testing program, most of them from 1961-1970. None, to my... 

Instead of determining the facts and circumstances of a specific wrong(s) or allegation(s), the mission was to conduct a form of historical research research which would determine exactly what the Army had done in chemical agent testing during the period 1950-1975. 

Comparison of peripheral and central potencies of belladonnoid agents tested in volunteers. Values are approximate and may differ slightly from those cited in text, due to insufficient data or variations in statistical methods employed. 

Data obtained by Shiberstoff (63) on the development of photographic film in solutions of conventional developers offer further evidence in confirmation of the latter point. Shiberstoff obtained a general increase in selectivity with decreasing temperature of development for all agents tested. He calculated selectivity in terms of the ratio of the rate of image development to fog formation, using as the rate of the former the reciprocal of the time required to attain a density of 1.5 for a fixed... 

SMANCS (Styrere-co-maleic acid/anhydride polymer bound to neocarzinostatin Neocarzinostatin (an antitumor protein) Amide bond between polymer carboxyl and protein amino None N/A SMANCS showed anticancer activity against many tumor cell lines, and had lower IC50 values than five other anticancer agents tested Liver tumors reduced more than 50% after 6 months in human subjects 15, 56, 57... 

Alkylation of Alkali Metal Cyanides by Alkyl Halides Activated in the a-Posi-tion by a Double Bond. When a mixture consisting of 4 to 8 moles of an alkyl halide activated in the apposition by a double bond is heated with 1 mole of alkali metal ferrocyanide, several alkylation products of the ferrocyanide anion can be isolated from the reaction mixture (12). The relative proportions of the tetra-, penta-, and hexaalkylated complexes can be varied by varying the alkyl halide to ferrocyanide ratio and the time of reaction. When potassium ferrocyanide is alkylated with benzyl bromide at a ratio of 4 alkyl halides to ferrocyanide anion, short reaction times favor the tetraalkylated complex an 8 to 1 ratio and long reaction times favor the hexaalkylated complex of the alkylating agents tested benzyl bromide provided the fastest alkylation ... 

In order to better access, utilize, and interpret existing teratology and reproduction toxicity data, a comprehensive data extraction project funded by the EPA is in progress at ETIC. Specific experimental data are extracted from selected ETIC master file documents. These data are entered in approximately 60 data fields, which comprise a data extraction file record. These data fields include information such as the identification of the test agent, test animals, experimental protocol, and results. Data field identifiers are listed in Table 6. 

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