Aethusa cynapium

Poison hemlock Conium maculatum) and dog parsley Aethusa cynapium) are poisonous plants of the parsley family, which contain coniine. 

FOOLS PARSLEY Aethusa cynapium, L., Family Apiaceae, is a European weed. The whole plant is poisonous due to the occurrence of very low content of the alkaloid coniine, a cicutoxin-like substance and essential oil. There have been lethal poisonings among humans and cattle. Symptoms of poisoning are stomach-ache, increased production of saliva, vomiting, diarrhoea, headache and blurred vision. 

It also occurs in the plant Aethusa cynapium L. (Apiaceae) (Fool s Parsley), Cicuta maculata L. Apiaceae) (water hemlock). 

Isol. from above-ground parts of Aethusa cynapium. Yellowish cryst. (pet. ether). Mp 68.5°. 

Amsinckia micrantha Conyza canadensis Descurainia sophia Aethusa cynapium Myosotis arvensis Digitalis purpurea Alopecurus pratensis Fritillaria meleagris Fumaria officinalis... 

Anthriscus sylvestris Aethusa cynapium Aphanes arvensis Sagina procumbens Thlaspi arvense Persicaria lapathifolia Matricaria disciodes Plantago major P. lanceolata Papaver rhoeas Eschscholzia califomica Primula vulgaris... 

Feeding experiments in Aethusa cynapium using [4,5- H2]trideca-l,4,ll-triene-7,9-diyne (52) have established that the biogenesis of aethusin (54) proceeds from (51) according to Scheme 5. Labelled (52) was found to be incorporated into both (53) and (54), and also into the 13-OH derivative of (54). 

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