Active moiety, definition

The question that emerges at the climax of this survey relates to the possibility of using crystalline inclusion phenomena for optical resolutions of molecular species. Can this be done effectively with suitably designed host compounds The definitely positive answer to this question has elegantly been demonstrated by Toda 20) as well as by other investigators (see Ch. 2 of Vol. 140). An optically active host compound will always form a chiral lattice. Therefore, when an inclusion type structure is induced, one enantiomer of the guest moiety should be included selectively within the asymmetric environment. 

The lone pair on arsenic is sterically active and the arsenic moiety is considered to be As03E (E = lone pair) rather than merely As03. Analysis of the X-ray data37 enables the definition of... 

Surfactants. By definition every detergent product contains one or more types of surfactants. Basically, every surfactant is an organic compound consisting of two parts (I) a hydrophobic portion, normally including a long hydrocarbon chain, and (2) a hydrophilic portion, which renders the entire compound sufficiently soluble or dispersible in water or other polar solvent to serve its intended use. Together, these combined hydrophobic and hydrophilic moieties render the compound surface-active—able to concentrate at the interface between a surfactant solution and another phase, such as air. soil, and textile substrate to be cleaned. 

Further studies are required to unravel this mystery of how the methoxy substitutions and the a, p-unsaturated p-diketone moiety actually influence conformational changes, lipophillicity, electron density distribution, and redox properties of curcuminoids. Correlating these physicochemical properties with the unique pleiotropic effects of curcuminoids is a rewarding exercise. Such studies would definitely provide proper reasoning in understanding these markedly different antioxidant, antitumor, and anti-inflammatory activities of natural curcuminoids from turmeric. 

This definition focuses on the processes by which the active ingredients or moieties are released from an oral dosage form and move to the site of action. 

A new class of water soluble cellulosic polymers currently receiving attention Is characterized by structures with hydrophobic moieties. Such polymers exhibit definite surface activity at alr-llquld and liquid-liquid Interfaces. By virtue of their hydrophobic groups, they also exhibit Interesting association characteristics In solution. In this paper, results are presented on the solution and Interfaclal properties of a cationic cellulosic polymer with hydrophobic groups and Its Interactions with conventional surfactants are discussed. 

When it is possible to identify a definite structural feature responsible for biological activity e.g. the sulfanilamide moiety in 39-42), the search for an efficient drug is expedited. Usually, however, the situation is far from being that simple. Structure-activity correlations are not that easy to establish. As an example, let us briefly consider the typical patterns of biological activity in steroids. 

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