Acrylonitrile Ritter reaction

CH3)2CH0H + CH2=C=0 CH3C00CH(CH3)2 and the Ritter reaction to prepare A/-isopropylacrylamide [2210-25-5] from acrylonitrile [107-13-1] and isopropyl alcohol ... 

Nafion beads, Nafion—Si02, and Aciplex-Si02 were tested by Okuhara and coworkers923 924 in the Ritter reaction between 1-adamantanol and acrylonitrile [Eq. 

Glikmans, G., Torek, B., Hellin, M., Coussemant, F. Ritter reaction between isobutene and acrylonitrile. II. Kinetic study. Butt. Soc. Chim. Fr. 1966, 1383-1388. 

NaAMB Series. 3-Acrylamido 3-methylbutanoic acid (AMBA) was synthesized via a Ritter reaction involving acrylonitrile and 3,3-dimethylacrylic acid in the presence of water and an excess of sulfuric acid. The synthesis basically followed the procedure set forth by Hoke and Robins. The crude product was twice recrystallized from a mixture of methyl ethyl ketone and petroleum ether prior to use (m.p. 89-91 C). The product was analyzed by elemental analysis and FTIR. Acrylamide was twice recrystallized from acetone prior to use. 

Other Sulfonic Acids. Extensive development work has been conducted on acrylic sulfonate-containing monomers. 2-Sulfoethyl methacrylate (SEM) monomer 5Ahas proved to be of limited commercial value owing to the hydrolytic instability of the ester linkage. However, recently well-defined homopolymers of 3-sulfopropyl methacrylate (SPMA) were prepared under aqueous RAFT conditions with 4-cyanopentanoic acid dithiobenzoate and V-501 as the CTA/initiator pair at 70°C (39). This same hydrolytic instability has been a serious problem with 3-sulfo-2-hydroxypropyl methacrylate. In contrast, 2-acrylamido-2-methylpropanesulfonic acid (AMPSA) 6A, prepared by the reactions of SO3 with isobutylene followed by the Ritter reaction with acrylonitrile (134), is quite hydrolytically stable. 

Other Anionic Carboxyiate Monomers. The anionic carboxylate monomers 8A and 9A, prepared by the Ritter reaction involving acrylonitrile or methacrylonitrile and 3,3-dimethylacrylic acid have been copolymerized in the sodium salt form to yield calcium-tolerant copoljnners with utility in enhanced oil recovery (145-148). Monomer 8A, for example, has been copol5unerized with 7A... 

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