Acrolein chloro

The general plan of Organic Syntheses has been discussed in the prefaces of the previous volumes. In this volume are published two distinctly different methods of preparation for each of two compounds. The directions for producing /3-chloro-propionic acid first from acrolein and second from trimethylene chlorohydrin, and for producing trimethylacetic acid first from terJ-butyl chloride and second from pinacolone, have been included. This has been deemed advisable since in some countries one raw material is more readily available than the other. 

Chloro-/3-(trifluoromethyl)acroleins reacted with 2-aminothiophenol at room temperature to give a mixture of a benzothiazole and quinoline. This was in contrast to the /3-methyl analogue, which gave a benzothiazep-ine, the difference being due to the electronic influence of the CF3 group (91TL643). 

Acetamido-4-amino-6-chloro-s-triazine, see Atrazine Acetanilide, see Aniline, Chlorobenzene, Vinclozolin Acetic acid, see Acenaphthene, Acetaldehyde, Acetic anhydride. Acetone, Acetonitrile, Acrolein, Acrylonitrile, Aldicarb. Amyl acetate, sec-Amyl acetate, Bis(2-ethylhexyl) phthalate. Butyl acetate, sec-Butyl acetate, ferf-Butyl acetate, 2-Chlorophenol, Diazinon. 2,4-Dimethylphenol, 2,4-Dinitrophenol, 2,4-Dinitrotoluene, 1,4-Dioxane, 1,2-Diphenylhydrazine, Esfenvalerate. Ethyl acetate, Flucvthrinate. Formic acid, sec-Hexyl acetate. Isopropyl acetate, Isoamyl acetate. Isobutyl acetate, Methanol. Methyl acetate. 2-Methvl-2-butene. Methyl ferf-butvl ether. Methyl cellosolve acetate. 2-Methvlphenol. Methomvl. 4-Nitrophenol, Pentachlorophenol, Phenol. Propyl acetate. 1,1,1-Trichloroethane, Vinyl acetate. Vinyl chloride Acetoacetic acid, see Mevinphos Acetone, see Acrolein. Acrylonitrile. Atrazine. Butane. 

The synthesis of 2-amino-5-chloromethyl-3-cyanopyrazine 1-oxide (529) from aminomalononitrile and chloromethyl hydroxyiminomethyl ketone, and of 2-amino-6-chloromethyl(and chloroalkyl)-3-cyanopyrazine 1-oxide (534) from aminomalononitrile and -chloro-a-hydroxyiminopropionaldehyde (prepared from the addition of nitrosyl chloride to acrolein) has been described in Section III.l. 

Other aldehydes and related compounds have been reacted either alone or catalyzed with sulfuric acid, zinc chloride, magnesium chloride, ammonium chloride, or diammonium phosphate (94). Compounds such as l,3-bis(hydroxymethyl)-2-imidazolidone, glycol acetate, acrolein, chloroacetaldehyde, heptaldehyde, o- and p-chloro-benzaldehydes, furfural, p-hydroxybenzaldehyde, and m-nitrobenz-aldehyde all achieve the ASE by a bulking mechanism and not by low-level cross-linking. At weight gains of 15-25%, the highest ASE reported is 40%. 

Perfluoroalkylbenzothiazoles are obtained by the reaction of 2-aminothio-phenol with fluorinated /1-diketones or /l-chloro-a -(trifluoromethyl)-acrolein (91TL643). With hydroxylamine, the products are 5-hydroxy-A2-isoxazolines (87GEP3603291). 

FERROUS AMMONIUM SULFATE (10045-89-3) Reacts violently with reducing agents, acrolein, alcohols, chlorine trifluoride, ethers, fluorine, hydrazine, hydrazinium perchlorate, hydrogen peroxide, finely divided aluminum or magnesium, ammonium perchlorate, mercury(II) dinitrate, peroxyfuroic acid, sodium acetylide, tetranitromethane. Sensitizes most organic azides that are unstable shock and heatexplosives. Forms explosive materials with l,3-di(5-tetrazoyl)triazene. Incompatible with glycidol, isopropyl chloro-carbonate, nitrosyl perchlorate, sodium borohydride. 

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