Acetylcholinesterase nematode

Arpagaus, M., Richier, P., Berge, J.-B. and Toutant, J.-P. (1992) Acetylcholinesterases of the nematode Steinemema carpocapsae. Characterization of two types of amphiphilic forms differing in their mode of membrane association. European Journal of Biochemistry 207, 1101-1108. 

Bremner, K.C., Ogilvie, B.M. and Berie, D.A. (1973) Acetylcholinesterase secretion by parasitic nematodes III. Oesophagostomum spp. International Journal for Parasitology 3, 609-618. 

Grauso, M., Culetto, E., Combes, D., Fedon, Y., Toutant, J.-P. and Arpagaus, M. (1998) Existence of four acetylcholinesterase genes in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. FEBS Letters 424, 279-284. 

Hussein, A.S., Chacon, M.R., Smith, A.M., Tosado-Acevedo, R. and Selkirk, M.E. (1999a) Cloning, expression and properties of a non-neuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis. Journal of Biological Chemistry 274, 9312-9319. 

Kolson, D.L. and Russell, R.L. (1985) A novel class of acetylcholinesterase, revealed by mutations, in the nematode Caenorhabditis elegans. Journal of Neurogenetics 2, 93-110. 

Lee, D.L. (1996) Why do some nematode parasites of the alimentary tract secrete acetylcholinesterase InternationalJournalfor Parasitology 26, 499-508. 

ACh, cholinomimetics and acetylcholinesterase inhibitors have been shown to inhibit the movement of flatworms and to cause flaccid paralysis (for reviews, see Fbx et a/., 1996 Halton et a/., 1997 Halton and Maule, 2004 Ribeiro et a/., 2005). This is in contrast to the mainly myoexcitatory effects of ACh at the vertebrate neuromuscular junction and in many other invertebrates including nematodes. Although ACh has predominantly inhibitory actions on flatworm muscle it has been shown to have inconsistent effects on the muscle of the monogenean, Diclidophora merlangi (Maule et a/., 1989), to induce the contraction of muscle fibres dispersed from planarians (Blair and Anderson, 1994 Moneypenny eta/., 2001) and, to cause increased muscle activity... 

Herman, R. K. and Kari, C. K. (1985) Muscle-specific expression of a gene affecting acetylcholinesterase in the nematode Caenorhabditis elegans. Cell. 40 509-514. 

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