Acetyl chloride reaction

Acetyl chloride, reaction with 2-acetamido-2-deoxy-D-glucose, 46, 1... 

Acetyl chloride, reaction with sodium formate, 50, 1 with propylene, aluminum chloride, and quinoline to give trans-3-pentene-2-one,... 

The conclusive proof that in acetone there are two methyl groups present is in the synthesis of acetone from acetic acid and acetyl chloride, reactions which we shall soon study. With this conclusive proof our formula, as we have written it, must be correct and our ideas in regard to the oxidation of compounds containing hydrogen linked to carbon are probably correct also. The steps in the oxidation are probably as we have indicated, viz., that hydrogen is first converted into hydroxyl and when as a result of such oxidation, two hydroxyls are linked to one carbon the compound loses water, leaving one oxygen doubly linked to the carbon. This enables us to understand the facts that only primary alcohols on oxidation yield aldehydes, secondary alcohols yield ketones, while tertiary alcohols yield neither aldehydes nor ketones. 

Figure 11. Catalytic activity as a function of the nature of the pillaring element for some pillared montmorillonites in the acylation of mesitylene with acetyl chloride (reaction temperature = 473 K reaetion time = 15 min AZA and FAZA supported by Concerted European Action-Pillared Layered Structures (CEA-PLS) EXM-534 and EXM-551 provided by Slid Chemie) [62].

Neutralization reactions have been followed by various techniques. A molybdenum electrode was found useful for potentiometric titrations in anhydrous thio-nyl chloride , but the mechanism of the electrode reaction has not been established. Likewise reactions between sulphur trioxide and various bases have been followed by conductometric and potentiometric titrations in solutions of acetyl chloride . Reactions in thionyl chloride can also be followed by the use of various colour indicators, such as methyl orange, methyl red, phenolphthalein, p-nitro-phenol, thymolphthalein or bromine thymolblue, which appear to be indicative of the chloride ion activities of the solutions. 

Scheme 4.38 Acetyl chloride reaction with pyridine.

---