Acetone dimethyl acetal

Acetone dimethyl acetal, reaction with n-butanol, 42,1... 

C5H 05 542-05-2) see Dolasetron mesilate Homatropine acetone dimethyl acetal... 

Acetonecarboxylic acid, a24 Acetone cyanohydrin, hi38a Acetone dimethyl acetal, d519 Acetone ketal of glycerin, d599 Acetonylacetone, h60... 

Dimethoxypropane Acetone, dimethyl acetal (8) Propane, 2,2-dimethoxy-(9) (77-76-9)... 

Acetone dimethyl acetal 15. acetone. PTSA, lllk over the two steps. 

Appropriately substituted hydroxy amides and ureas can be used instead of diamines. Thus, acid-catalyzed cyclocondensation of iV-carbamoyl prolinols 137 (R1 = H, (CH2)3) (Scheme 27) with aldehydes RCHO (R = Ph, 2-MeOC6H4, 2-naphthyl, etc.) stereoselectively afforded a series of pyrroldine-fused oxadiazepinones 46 (Scheme 5) <1990CPB2627, 1990H(30)287, 1996LA927>. Similar heterocyclization of 4-(2-hydroxyethylthio)-2-azetidinone with acetone dimethyl acetal was used in the synthesis of azetidinone-fused oxathiazepanes of type 33 (X = S) (Figure 4) <1980JA2039>. 

Erythorblc acid O-erythro-Hex-2-enolc acid, y-lactone (8,9) (89-65-6) 2,2-Dimethoxypropane Acetone, dimethyl acetal (8) Propane, 2,2-dimethoxy-(9) (77-76-9)... 

More recently, the present author examined the mechanism of bromination of acetone-acetone dimethyl acetal mixtures in methanol containing small... 

A mixture of 312 g. (3 moles) of acetone dimethyl acetal (Note 1), 489 g. (6.6 moles) of butanol, 1.0 1. of benzene, and 0.2 g. of / -toluenesulfonic acid is placed in a 3-1. flask. The flask is connected to a packed fractionating column and the solution distilled until the azeotrope of benzene and methanol, boiling at 58°, is completely removed (Note 2). The contents of the boiler are then cooled below the boiling point and a solution of 0.5 g. of sodium methoxide in 20 ml. of methanol (Note 3) is added all at once with stirring. The flask is replaced for further distillation, and most of the remaining benzene is distilled at atmospheric pressure. The pressure is then reduced, and the remaining benzene and imreacted butanol are removed (Note 4). Finally, the pressure is reduced to 20 mm., the last traces of low-boiling materials are taken to the cold trap, and the product is distilled. After a small fore-run, acetone dibutyl acetal is collected at 88-90°/20 mm. The yield is 421-453 g. (74.6-80.3%), 1.4105, df 0.8315. 

Commercial acetone dimethyl acetal (2,2-dimethoxypro-pane) from the Dow Chemical Company was used without further treatment. 

Commercial acetone dimethyl acetal and allyl alcohol from The Dow Chemical Company and cyclohexanone from Eastman Kodak Company were used without further treatment. 

The most important and widely used ketal is the acetonide. It is prepared by the reaction of the diol with acetone " or acetone dimethyl acetal and an acid catalyst. Also 2-alkoxy and 2-silyloxy propenes can be applied for this purpose (Scheme 49). ° In the reactions with carbohydrates fiiranose rings are formed if possible, but under kinetically controlled conditions also 1,3-dioxanes may be constructed. In the cases of hexoses which do not contain cw-l,2-diols the reaction usually involves toe 6-OH group. 

A further method of preparing methyl esters was provided by Lorette and Brown Jr.804 who used acetone dimethyl acetal as water-binding agent ... 

Carbonates and carbamates. In the presence of phosphine-CBr4 and base, alcohols combine with CO2 to afford carbonates. Mixed carbonates are obtained under different conditions, and with a Mg—A1 mixed oxide as catalyst, epoxides formed cyclic carbonates. The preparation of dimethyl carbonate from acetone dimethyl acetal and supercritical carbon dioxide in the presence of a metal catalyst (e.g., dibutyltin methoxide) is successfully carried out. ... 

Adipic acid (585 g, 4 mol) was added to 200 mL methanol containing 5 g p-toluenesulfonic acid. This mixture was stirred in a 2-L flask and maintained at 40-60°C. As the reaction progressed, acetone dimethyl acetal was added in increments. By the end of 30 min, 200 mL had been added, by the end of 1 h, 600 mL total had been added (at this point, all adipic acid was in solution), and by the end of 1.5 h, a total of 1 L of the acetone dimethyl acetal (8 mol) had been added. At the end of 2 h, only 10% of the acid remained unreacted. After 4 h, the reaction was 99% complete. One half of the crude solution was then distilled at a rate such that by the end of 3 h, all of the acetone and methanol had been removed. This left a 98.8% yield of crude, straw-colored dimethyl adipate. On further distillation, a 94% yield of pure dimethyl adipate with a boiling point of 109°C was recovered. 

Acetone, acetonyl-. See 2,5-Hexanedione Acetone chloroform. See Chlorobutanol hemihydrate Chlorobutanol Acetone cyanhydrin Acetone cyanohydrin. See 2-Hydroxy-2-methylpropanenitrile Acetonedicarboxylic acid Acetone-1,3-dicarboxylic acid. See P-Ketoglutaric acid Acetone dimethyl acetal. See Dimethoxypropane Acetone/diphenylamine condensate Acetone/diphenylamine condensates. See Di phenylam i ne-acetone Acetone/formaldehyde condensate CAS 25619-09-4 Uses In food-pkg. adhesives Regulatory FDA 21CFR 175.105... 

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