Acetic acetone

Allow a mixture of 0-5 g. of the tertiary amine and 0-5 ml. of colourless methyl iodide to stand for 5 minutes. If reaction has not occurred, warm under reflux for 5 minutes on a water bath and then cool in ice water. The mixture will generally set solid if it does not, scratch the sides of the tube with a glass rod. RecrystaUise the solid product from absolute alcohol, ethyl acetate, acetone, glacial acetic acid or alcohol-ether. 

This material Is purified by recrystallization from ethyl acetate acetone 2 1 (v v) to give a first crop (6.8 g), and by flash chromatography of the residue from the mother liquor, using 150 g of 230-400 mesh silica gel (Merck), a 40-mm diameter column, and elution with 10 1 (v v) ethyl acetate methanol. A fast moving orange band and a slower moving lemon-yellow band can be clearly seen on the column. The lemon-yellow hand is collected from the column and evaporation gives a second crop (1.4 g) of comparably pure material. The total yield of the pale yellow isoquinoline is 8.2 g (86t), mp 135-137°C (Note 10). 

Alumina used in TLC can be recovered by washing in ethanol for 48h with occasional stirring, to remove binder material and then washed with successive portions of ethyl acetate, acetone and finally with distilled water. Fine particles are removed by siphoning. The alumina is first suspended in 0.04M acetic acid, then in distilled water, siphoning off 30 minutes after each wash. The process is repeated 7-8 times. It is then dried and activated at 200° [Vogh and Thomson Anal Chem 53 1365 1981],... 

Abbreviations Acet, acetone TFA, trifluoroacetic acid Py, pyridine. 

Acetone is a volatile liquid with a distinct sweet odor. It is miscible with water, alcohols, and many hydrocarbons. For this reason, it is a highly desirable solvent for paints, lacquers, and cellulose acetate. Acetone was the 41st highest volume chemical. The 1994 U.S. production was approximately 2.8 billion pounds. 

Mobile phase Ethyl acetate — acetone — ammonia (25%) (6 -F 6 -F 1). 

The most critical decision to be made is the choice of the best solvent to facilitate extraction of the drug residue while minimizing interference. A review of available solubility, logP, and pK /pKb data for the marker residue can become an important first step in the selection of the best extraction solvents to try. A selected list of solvents from the literature methods include individual solvents (n-hexane, " dichloromethane, ethyl acetate, acetone, acetonitrile, methanol, and water ) mixtures of solvents (dichloromethane-methanol-acetic acid, isooctane-ethyl acetate, methanol-water, and acetonitrile-water ), and aqueous buffer solutions (phosphate and sodium sulfate ). Hexane is a very nonpolar solvent and could be chosen as an extraction solvent if the analyte is also very nonpolar. For example, Serrano et al used n-hexane to extract the very nonpolar polychlorinated biphenyls (PCBs) from fat, liver, and kidney of whale. One advantage of using n-hexane as an extraction solvent for fat tissue is that the fat itself will be completely dissolved, but this will necessitate an additional cleanup step to remove the substantial fat matrix. The choice of chlorinated hydrocarbons such as methylene chloride, chloroform, and carbon tetrachloride should be avoided owing to safety and environmental concerns with these solvents. Diethyl ether and ethyl acetate are other relatively nonpolar solvents that are appropriate for extraction of nonpolar analytes. Diethyl ether or ethyl acetate may also be combined with hexane (or other hydrocarbon solvent) to create an extraction solvent that has a polarity intermediate between the two solvents. For example, Gerhardt et a/. used a combination of isooctane and ethyl acetate for the extraction of several ionophores from various animal tissues. 

For the extraction of rubber and rubber compounds a wide variety of solvents (ethyl acetate, acetone, toluene, chloroform, carbon tetrachloride, hexane) have been used [149]. Soxtec extraction has also been used for HDPE/(Tinuvin 770, Chimassorb 944) [114] and has been compared to ultrasonic extraction, room temperature diffusion, dissolution/precipitation and reflux extraction. The relatively poor performance of the Soxtec extraction (50% after 4h in DCM) as compared with the reflux extraction (95% after 2-4 h in toluene at 60 °C) was described to the large difference in temperature between the boiling solvents. Soxtec was also used to extract oil finish from synthetic polymer yam (calibration set range of 0.18-0.33 %, standard error 0.015 %) as reference data for NIRS method development [150]. 

In the resulting binary solvent mixtures of either OSM or TSM micronising step procedures, one apolar component (n-hexane or n-heptane) serves to give high swelling-melting power to the polymer but does not heat under microwave irradiation. The second polar component (ethyl acetate, acetone, and isopropyl alcohol) has... 

Results of liquid phase NMR measurements (Table 4) show that only the real substrates influences the proton shift of H3 and H9 protons of CD. These data confirmed the liquid phase interaction between the diketones and the chiral modifier. No effect of dummy substrates (ethyl acetate, acetone, etc.) was observed. No direct connection was found between kinetic data (reaction rate and optical yield) and NMR proton shift. Liquid phase NMR measurements confirmed the interaction of both 2,3-butandione and 3,4-hexanedione with the alkaloid used. 

Rapid-acting dermally hazardous cytotoxin that inhibits protein synthesis and affects clotting factors in the blood. It is capable of producing incapacitating or lethal effects. T2 is obtained from various molds and fungi (Fusarium sp.). It is a colorless crystalline solid of white powder that melts at 304°F. Impure samples may be a colorless to slightly yellow oil. It is slightly soluble in water, but soluble in ethyl acetate, acetone, ethanol, chloroform, methylene chloride, diethyl ether, and dimethyl sulfoxide (DMSO). It is heat stable and can be stored at room temperature for years. 

Specific surface area (m2/g) Ethanol Toluene Butyl acetate Acetone Dibutyl phthalate... 

A similar RP-HPLC method has been developed for the determination of isoflavones in soybean powder. Ground soybean powder (100 g) was extracted four times with 300 ml of hexane, then the defatted powder was extracted with six solvents or solvent mixtures such as acetone, methanol-water (4 1, v/v), methanol-ethyl acetate-acetone (1 1 1, v/v), acetone-0.1 M HC1 (5 1, v/v), methanol-water (4 1, v/v) plus 0.1 M HC1 (5 1, v/v), and methanol-ethyl acetate-acetone (1 1 1, v/v) plus 0.1 M HC1 (5 1, v/v). An aliquot of 0.5 g defatted or non-defatted soybean powder was shaken for 2h or sonificated for lh with 5 ml... 

Myristic add from myristic add, lauric add Silicalite-1 Methyl acetate, acetone, 3-pentanone [207]... 

Number Acetate Acetone Specific Gravity beginning end... 

Let US use a systematic approach to consider what product is most likely to result when a mixture of an ester and a ketone, both capable of forming enolate anions, is treated with base. For example, consider an ethyl acetate-acetone mixture treated with sodium hydride in ether solution. 

The purification of bacterial constituents usually starts in a very conventional way with an extraction step of the crude broth at neutral or slightly acidic pH. Mycelium-forming organisms are separated by filtration, and the cell mass and the filtrate are extracted separately. For the liquid phase, adsorber resins allow high recovery rates of metabolites and low process costs due to repeated use of the resins. If liquid-liquid extraction has to be applied, medium or highly polar solvents are favored. Ethyl acetate is the solvent of choice, and only in few cases is butanol superior. To extract the moist cell material, ethyl acetate, acetone or dichloromethane/methanol can be used. 

Virginiamycin is a mixture of two components designated Mi and Si, which are both cyclic polypeptides. It is soluble in methanol, ethanol, acetic acid, ethyl acetate, acetone, chloroform, and benzene but is practically insoluble in water and dilute acid. It also dissolves in alkalis but is rapidly deactivated. 

N 26.41% OB to COa +15.1% crysts, mp 59—60° bp — expl at higher temp sol in methanol, eth, et acet, acetone, NMe and doxane si sol in benz chlf insol in w was obtd by Chute et al on treating with 99% nitric acid some of the products isolated on nitrolysis of hexamine... 

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