Acetone Chlorobutanol

In the presence of an alkali metal hydroxide at about 50°C, chloroform condenses with acetone to give l,l,l-trichloro-2-methyl-2-propanol, [57-15-8] ie, chlorobutanol, chloretone, or acetone—chloroform (9,10). Chlorobutanol is a white crystalline substance with a campborlike odor its sedative, anesthetic, and antiseptic properties have given the compound some importance in the pharmaceutical industry. 

Chlorobutanol is prepared by condensing acetone and chloroform in the presence of solid potassium hydroxide. 

Acetone, acetonyl-. See 2,5-Hexanedione Acetone chloroform. See Chlorobutanol hemihydrate Chlorobutanol Acetone cyanhydrin Acetone cyanohydrin. See 2-Hydroxy-2-methylpropanenitrile Acetonedicarboxylic acid Acetone-1,3-dicarboxylic acid. See P-Ketoglutaric acid Acetone dimethyl acetal. See Dimethoxypropane Acetone/diphenylamine condensate Acetone/diphenylamine condensates. See Di phenylam i ne-acetone Acetone/formaldehyde condensate CAS 25619-09-4 Uses In food-pkg. adhesives Regulatory FDA 21CFR 175.105... 

CAS 57-15-8 EINECS/ELINCS 200-317-6 Synonyms Acetone chloroform Anhydrous chlorobutanol Chlorbutanol Chlorbutol Chloretone... 

Chlorobutanol hemihydrate CAS 6001-64-5 EINECS/ELINCS 200-317-6 Synonyms Acetone chloroform p,p,p-Trichloro-t-butyl alcohol 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate Empirical C4H7CI3O Y2H20 Formula Cl3CC(CH3)20H Y2H2O Properties M.w. 186.46 Uses Antimicrobial, preservative for pharmaceuticals... 

Chlorobutanol (chlorbutanol, trichlorbutanol, chlorbutol, acetone chloroform, Chloretone, Coli-quifilm, Methaform, Sedaform, CAS no. 57-15-8). This is an antimicrobial used in pharmaceutical preparations. It is also a mild sedative. The patch-test concentration is 5% pet (Hannuksela et al. 

Chlorobutanol n (chlorbutanol, l,l,l-trichloro-2-methyl-2-propanol, acetone chloroform, trichloro-tert-butyl alcohol) Cl3CC(CH3)20H. A plasticizer for esters and ethers of cellulose. 

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