Blockers a-adrenergic

The ergolines have provided a number of drugs that show interaction with neurotransmitters. Depending on the substitution pattern, they may be dopamine agonists or antagonists, a-adrenergic blockers, or Inhibitors of the release of prolactin. A recent member of the series, pergolide... 

The six main drug classes used, worldwide, for blood pressure lowering treatment are diuretics, jS-blockers, calcium channel blockers (CCB), ACE inhibitors, angiotensin II (All) receptor blockers and a-adrenergic blockers. In some parts of the world, reserpine and methyldopa are also frequently used. 

Hypertensive crises are characterized initially by headache, but can evolve to include neck stiffness, chest discomfort, palpitations, confusion, and, ultimately, hemorrhage or stroke. Treatment of MAOI-associated hypertension may include a watch-and-wait stance by the patient if the symptoms are mild. Some patients have the ability to check and monitor their own blood pressure. Others may consult with a physician for blood pressure checks and observation, but if symptoms are severe, the patient may need to go to an emergency room or self-medicate. Standard emergency room treatment is intravenous phentolamine, an a-adrenergic blocker, continuous monitoring and management until blood pressure is normalized without medication. Some doctors will provide patients with small doses of chlorpromazine or nifedipine to treat hypertension if a problem arises. 

Attachment of a base-bearing side chain to the carbocyclic ring of a benzodioxan gives another compound that acts as an a-adrenergic blocker. Mannich reaction of the methyl ketone in (61-2), obtainable by acetylation of the benzodioxan proper (61-1), with phenylpyrrolidine (61-3) and formaldehyde leads directly to proroxan (61-4) [71]. 

On the other hand, very often the observed effect is measured a long way downstream of the dmg receptor, as in our example of smoth muscle contraction and a-adrenergic blockers. Other such examples are... 

More correctly, a -adrenergic blocker. See indications, side effects, and adverse reactions at, for example, httpy/www.rxlist.com/bblock.htm Known in the United States as norepinephrine. 

Doxazosin a-Adrenergic blocker, Blocks ai-adrenergic receptor,... 

Doxazosin Doxazosina Doxazosine Doxazosinum UK 33274, Selective a-adrenergic blocker related to Prazosin. Antihypertensive. Also used in the treatment of benign prostatic hyperplasia, [monohydrochloride] mpn 289-290". Pfizer Inti. Roerig Div. Pfizer Pherm. 

Vinorelbine Yohimbine la(corynanthean) Corynanthe johimbe a-adrenergic blocker... 

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