Corynanthe johimbe

Yohimbine Yohimbine is methyl ether ( )-2a-hydroxyyohimban-la-carboxylic acid (12.2.16). It is isolated from the plants Corynanthe johimbe and Rauwolfia serpentina [60,61], It is also synthesized [62-66],... 

Pausinystalia yohimbe Pierre (Corynanthe johimbe K. Sehum.)... 

Yohimbine, (16a,I7a) 17-Hydroxyyohimban-I6-carboxylic acid methyl ester quebrachine corynine aphro-dine, C, HuNiOJ mol wt 354.43. C 71.16%, H 7,39%, N 7.90%, O 13.54%. Indole alkaloid with a,-adrenergic blocking activity. Found in Corynanthe johimbe K. Schum., Rubiaceae and related trees, also in Rauwolfla serpentina (L.) Benth., Apocynaceae Raymond -Hamet. J. Pharm. Chim. 

Vinorelbine Yohimbine la(corynanthean) Corynanthe johimbe a-adrenergic blocker... 

Y. is the main alkaloid of many Aspidosperma species, it also occurs in Rubiaceae such as Corynanthe johimbe i=Pausinystalia) and related trees as well as in some Apocynaceae (e. g., Rauvolfia and Vinca species). Y. is structurally related to the Rauvolfia alkaloids, e. g., reserpine. Y. is the methyl ester of yohimb(in)ic acid (C20H24N2O3, Mr 340.42, mp. 280-300°C). In medicine Y. is used especially in the form of its more water-soluble hydrochloride (decomp. at 302 °C) as a... 

Pausinystalia yohimba Corynanthe johimbe) (Rubiaceae) is an evergreen tree that grows wild in the southern areas of Africa, and is known locally as yohimbe. The bark of P. yohimba has been used as an aphrodisiac drug for centuries. 

Uncaria tomentosa (Pedaliaceae), Corynanthe pachyceras, Pausinystalia johimbe (Rubiaceae) [bark] Semi-synthetic... 

The stem bark of P. yohimbe (= P. johimbe Corynanthe yohimbe), "yohimbe as it is known in Cameroon, Gabon and Congo is used traditionally as an aphrodisiac and stimulant to prevent sleep (41). The bark contains 1-6% of indole alkaloids, most of which are yohimbane-type alkaloids, the main one being yohimbine [7], which is structurally related to reserpine [8] (89). Yohimbine is a selective inhibitor of a-2- adrenergic receptors and, while at low dose it has hypertensive activity, at high dose it is hypotensive (vasodilation of peripheral vessels). It is the vasodilation of peripheral vessels, and especially vasodilation of the corpus cavemosum, which is the cause of the reputation of yohimbine as an aphrodisiac (90). Tests have shown, indeed, that increased... 

Source Pausinystalia yohimba Pierre ex Beille. P. johimbe (Schumann) Beille, Corynanthe johimbi Schumann) (Family Rubiaceae). 

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